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. 2018 Mar 12;16(1):44.
doi: 10.1186/s12955-018-0873-3.

Vitamin D deficiency is associated with poorer satisfaction with diabetes-related treatment and quality of life in patients with type 2 diabetes: a cross-sectional study

Nuria Alcubierre  1 , Esmeralda Castelblanco  2   3 , Montserrat Martínez-Alonso  4 , Minerva Granado-Casas  2   5 , Aureli Esquerda  6 , Alicia Traveset  5   7 , Dolores Martinez-Gonzalez  5 , Josep Franch-Nadal  3   8   9 , Didac Mauricio  10   11   12
Affiliations

Vitamin D deficiency is associated with poorer satisfaction with diabetes-related treatment and quality of life in patients with type 2 diabetes: a cross-sectional study

Nuria Alcubierre et al. Health Qual Life Outcomes. .

Abstract

Background: In this cross-sectional study, we assessed the possible association of vitamin D deficiency with self-reported treatment satisfaction and health-related quality of life in patients with type 2 diabetes.

Methods: We performed a sub-analysis of a previous study and included a total of 292 type 2 diabetic patients. We evaluated treatment satisfaction and health-related quality of life through specific tools: the Diabetes Treatment Satisfaction Questionnaire and the Audit of Diabetes-Dependent Quality of Life. Vitamin D deficiency was defined as 25 (OH) D serum levels < 15 ng/mL.

Results: Multivariable linear regression models were used to estimate the relationship of vitamin D deficiency with both outcomes once adjusted for self-reported patient characteristics. Vitamin D deficiency was significantly associated with the final score of the Diabetes Treatment Satisfaction Questionnaire and the single "diabetes-specific quality of life" dimension of the Audit of Diabetes-Dependent Quality of Life (p = 0.0198 and p = 0.0070, respectively). However, lower concentrations of 25-OH vitamin D were not associated with the overall quality of life score or the perceived frequency of hyperglycaemia and hypoglycaemia.

Conclusions: Our study shows the association between vitamin D deficiency and both the self-reported diabetes treatment satisfaction and the diabetes-specific quality of life in patients with type 2 diabetes.

Keywords: Diabetic retinopathy; Health-related quality of life; Treatment satisfaction; Type 2 diabetes mellitus; Vitamin D.

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Conflict of interest statement

Competing interest

The authors declare that they have no competing interests.

Ethics approval and consent to participate

Ethics approval was obtained from the Human Research Ethics Committee of University Hospital of Arnau de Vilanova (Lleida) with the reference number 12/2009, in accordance with the Declaration of Helsinki, and informed consent to participate was obtained from each patient included in the investigation.

Consent for publication

Not applicable.

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