Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Jan;79(1):e14-e18.
doi: 10.1055/s-0038-1637006. Epub 2018 Mar 9.

Rapidly Expanding Lateral Ventricular Meningioma Presenting with Intraventricular Hemorrhage following Remote Whole Brain Radiation and Stereotactic Radiosurgery

Joshua T Prickett  1   2   3   4   5 , Brendan J Klein  1   2   3   4   5 , Christopher M Busch  1   2   3   4   5 , Joshua A Cuoco  6 , Lisa S Apfel  1   2   3   4   5 , Eric A Marvin  1   2   3   4   5
Affiliations
Case Reports

Rapidly Expanding Lateral Ventricular Meningioma Presenting with Intraventricular Hemorrhage following Remote Whole Brain Radiation and Stereotactic Radiosurgery

Joshua T Prickett et al. J Neurol Surg Rep. 2018 Jan.

Abstract

Intraventricular meningiomas are uncommon intracranial tumors and infrequently present with hemorrhage. With only 10 reported cases in the literature, it is exceedingly rare for meningiomas of the ventricular system to present with hemorrhage. To our knowledge, this is the first report of a patient presenting with an acute intraventricular hemorrhage in relation to a ventricular meningioma suspected to be radiation induced. In addition, we review the current literature on hemorrhagic intraventricular meningiomas and review the natural history of radiation-induced meningiomas.

Keywords: intraventricular hemorrhage; meningioma; ventricular system; whole brain radiation.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
These images are from 8 years prior to presentation. ( A ) T1-weighted axial magnetic resonance imaging (MRI) with contrast showing the lateral ventricles normal in size and midline in position. ( B ) T2 fast low angle shot (FLASH) MRI demonstrating a 7 mm cavernous angioma within the upper left corona radiata. Considerable signal hypodensity is observed at the periphery of this lesion consistent with abundant hemosiderin deposition secondary to hemorrhage. ( C ) T2 FLASH MRI demonstrating a 9 mm cavernous angioma within the central portion of the midbrain, immediately anterior to the cerebral aqueduct. Considerably less extensive signal hypointensity is observed at the periphery of the midbrain lesion.
Fig. 2
Fig. 2
Axial computed tomography of the head demonstrating a round homogeneous isodensity within the right lateral ventricle. Hyperdense acute hemorrhage within the ventricular and intraparenchymal spaces was observed.
Fig. 3
Fig. 3
T1-weighted axial magnetic resonance imaging demonstrating a T1 hypointense lesion measuring 4.2 cm craniocaudal, 3.2 cm anteroposteriorly, and 3.2 cm transverse in dimensions.
Fig. 4
Fig. 4
Histological examination showed a spindle/fibroblastic tumor. Ki67, performed to assess proliferative activity, was < 1%. This was consistent with a grade I meningioma, meningothelial subtype.
See this image and copyright information in PMC

References

    1. Saraf S, McCarthy B J, Villano J L. Update on meningiomas. Oncologist. 2011;16(11):1604–1613. - PMC - PubMed
    1. Nakamura M, Roser F, Bundschuh O, Vorkapic P, Samii M.Intraventricular meningiomas: a review of 16 cases with reference to the literature Surg Neurol 20035906491–503., discussion 503–504 - PubMed
    1. Bosnjak R, Derham C, Popović M, Ravnik J. Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome. J Neurosurg. 2005;103(03):473–484. - PubMed
    1. Askenasy H M, Behmoaram A D. Subarachnoid hemorrhage in meningiomas of the lateral ventricle. Neurology. 1960;10:484–489. - PubMed
    1. Goran A, Cimenello V J, Fisher R G. Hemorrhage into meningiomas. Arch Neurol. 1965;13:65–69. - PubMed

Publication types