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. 2018 Feb 28;4(2):137-139.
doi: 10.1021/acscentsci.8b00045. Epub 2018 Jan 31.

Gapping into Ultrahigh Surface-Enhanced Raman Scattering Amplification

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Gapping into Ultrahigh Surface-Enhanced Raman Scattering Amplification

Kang Yong Loh et al. ACS Cent Sci. .
No abstract available

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Figures

Figure 1
Figure 1
Schematic showing the SERS effect of an intra-nanogap inside a gold nanoparticle on Raman reporter molecules that are conjugated to the nanogap interface.
Figure 2
Figure 2
Dealloyed intra-nanogap particles (DIPs) for SERS biosensing and bioimaging applications. (A) Transmission electron microscopic image of SERS-active DIPs. (B) High-magnification electron microscopic imaging of a typical DIP. (C) SERS enhancement factors obtained with DIPs. (D) SERS intensity profiles obtained for DNA sensing at different concentrations using DIPs. (E) Sketch of the experimental setup for DIP-based molecular sensing and cellular imaging. Reproduced with permission from ref (5). Copyright 2018 American Chemical Society.

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References

    1. Fleischmann M.; Hendra P. J.; McQuillan A. J. Raman spectra of pyridine adsorbed at a silver electrode. Chem. Phys. Lett. 1974, 26, 163–166. 10.1016/0009-2614(74)85388-1. - DOI
    1. Laing S.; Jamieson L. E.; Faulds K.; Graham D. Surface-enhanced Raman spectroscopy for in vivo biosensing. Nat. Rev. Chem. 2017, 1, 0060. 10.1038/s41570-017-0060. - DOI
    1. Qian X. M.; Nie S. M. Single-molecule and single-nanoparticle SERS: from fundamental mechanisms to biomedical applications. Chem. Soc. Rev. 2008, 37, 912–920. 10.1039/b708839f. - DOI - PubMed
    1. Fang Y.; Seong N.-H.; Dlott D. D. Measurement of the Distribution of Site Enhancements in Surface-Enhanced Raman Scattering. Science 2008, 321, 388. 10.1126/science.1159499. - DOI - PubMed
    1. Kim M.; Ko S. M.; Kim J.-M.; Son J.; Lee C.; Rhim W.-K.; Nam J.-M. Dealloyed Intra-Nanogap Particles with Highly Robust, Quantifiable Surface-Enhanced Raman Scattering Signals for Biosensing and Bioimaging Applications. ACS Cent. Sci. 2018, 10.1021/acscentsci.7b00584. - DOI - PMC - PubMed

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