Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2018 Apr;128(4):700-703.
doi: 10.1097/ALN.0000000000002121.

Anesthesia and Neurodevelopment in Children: Perhaps the End of the Beginning

David O Warner  1 , Yu Shi, Randall P Flick
Affiliations
Editorial

Anesthesia and Neurodevelopment in Children: Perhaps the End of the Beginning

David O Warner et al. Anesthesiology. 2018 Apr.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors declare no competing interests.

Figures

Figure 1
Figure 1
Example of a conceptual framework describing potential factors that affect outcomes after procedures requiring anesthesia. Peri-procedural and contextual factors interact to determine acute child responses to the procedure; early and longer term responses in affect, behavior, and cognitive abilities continue to be moderated by these contextual factors as they evolve.
See this image and copyright information in PMC

Comment in

  • The Challenges of Translation.
    Kharasch ED. Kharasch ED. Anesthesiology. 2018 Apr;128(4):693-696. doi: 10.1097/ALN.0000000000002122. Anesthesiology. 2018. PMID: 29533965 No abstract available.

Comment on

References

    1. Davidson AJ, Sun LS. Clinical evidence for effects of anesthesia on the developing brain. Anesthesiology. 20X XX: XXX. - PubMed
    1. Andropoulos DB, Greene MF. Anesthesia and Developing Brains - Implications of the FDA warning. N Engl J Med. 2017;376:905–907. - PubMed
    1. Stargatt R, Davidson AJ, Huang GH, Czarnecki C, Gibson MA, Stewart SA, Jamsen K. A cohort study of the incidence and risk factors for negative behavior changes in children after general anesthesia. Paediatr Anaesth. 2006;16:846–59. - PubMed
    1. Hansen TG, Lonnqvist PA. The rise and fall of anaesthesia-related neurotoxicity and the immature developing human brain. Acta Anaesthesiol Scand. 2016;60:280–3. - PubMed
    1. Rauh VA, Margolis AE. Research Review: Environmental exposures, neurodevelopment, and child mental health - new paradigms for the study of brain and behavioral effects. J Child Psychol Psychiatry. 2016;57:775–93. - PMC - PubMed