Evaluation of the Cepheid^® Xpert^®C. difficile binary toxin (BT) diagnostic assay

Alan M McGovern¹, Grace O Androga², Peter Moono¹, Deirdre A Collins³, Niki F Foster⁴, Barbara J Chang¹, Thomas V Riley⁵

Affiliations

¹ School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
² School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia; Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia.
³ School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
⁴ OzFoodNet, Communicable Disease Control Directorate, Department of Health, Government of Western Australia, East Perth, Western Australia, Australia.
⁵ Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia; School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia. Electronic address: thomas.riley@uwa.edu.au.

PMID: 29534914
DOI: 10.1016/j.anaerobe.2018.03.004

Evaluation of the Cepheid^® Xpert^®C. difficile binary toxin (BT) diagnostic assay

Alan M McGovern et al. Anaerobe. 2018 Jun.

. 2018 Jun:51:12-16.

doi: 10.1016/j.anaerobe.2018.03.004. Epub 2018 Mar 11.

Authors

Alan M McGovern¹, Grace O Androga², Peter Moono¹, Deirdre A Collins³, Niki F Foster⁴, Barbara J Chang¹, Thomas V Riley⁵

Affiliations

¹ School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
² School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia; Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia.
³ School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
⁴ OzFoodNet, Communicable Disease Control Directorate, Department of Health, Government of Western Australia, East Perth, Western Australia, Australia.
⁵ Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia; School of Veterinary and Life Sciences, Murdoch University, Murdoch, Western Australia, Australia. Electronic address: thomas.riley@uwa.edu.au.

PMID: 29534914
DOI: 10.1016/j.anaerobe.2018.03.004

Abstract

Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

Keywords: Binary toxin; CDT; Clostridium difficile infection; Diagnostics; Piglets.

PubMed Disclaimer

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science
Other Literature Sources
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Evaluation of the Cepheid^® Xpert^®C. difficile binary toxin (BT) diagnostic assay

Affiliations

Evaluation of the Cepheid^® Xpert^®C. difficile binary toxin (BT) diagnostic assay

Authors

Affiliations

Abstract

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources