Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Feb;33(1):21-43.
doi: 10.1007/s12250-018-0019-0. Epub 2018 Mar 13.

Tick-Borne Viruses

Junming Shi  1 , Zhihong Hu  1 , Fei Deng  2 , Shu Shen  3
Affiliations
Review

Tick-Borne Viruses

Junming Shi et al. Virol Sin. 2018 Feb.

Abstract

Ticks are important vectors for the transmission of pathogens including viruses. The viruses carried by ticks also known as tick-borne viruses (TBVs), contain a large group of viruses with diverse genetic properties and are concluded in two orders, nine families, and at least 12 genera. Some members of the TBVs are notorious agents causing severe diseases with high mortality rates in humans and livestock, while some others may pose risks to public health that are still unclear to us. Herein, we review the current knowledge of TBVs with emphases on the history of virus isolation and identification, tick vectors, and potential pathogenicity to humans and animals, including assigned species as well as the recently discovered and unassigned species. All these will promote our understanding of the diversity of TBVs, and will facilitate the further investigation of TBVs in association with both ticks and vertebrate hosts.

Keywords: Identification; Isolation; Tick-borne viruses (TBVs); Ticks.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest

The authors declare that they have no conflict of interest.

Animal and Human Rights Statement

This article does not contain any studies with human or animal subjects performed by any of the authors.

Figures

Fig. 1
Fig. 1
Taxonomy of tick-borne viruses. The classification of currently known tick-borne viruses was summarized in open circles which present orders, families, genera, and species of the viruses from the inner to the outer circle, respectively.
See this image and copyright information in PMC

References

    1. Abramova LF, Terskikh II, Terskikh IF, Gromashevskii VL, Gromashevskii VF, L’Vov DK. Comparative characteristics of the pathogenicity of 2 viruses of the family Rhabdoviridae for monkeys. Vopr Virusol. 1987;2:357–359. - PubMed
    1. Afonso CL, Amarasinghe GK, Banyai K, Bao Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Cheng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Durrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astua J, Formenty P, Fouchier RA, Fu Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liu L, Longdon B, Marton S, Maisner A, Muhlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xie JT, Yuen KY, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2016. Arch Virol. 2016;161:2351–2360. doi: 10.1007/s00705-016-2880-1. - DOI - PMC - PubMed
    1. Alberdi MP, Dalby MJ, Rodriguez-Andres J, Fazakerley JK, Kohl A, Bell-Sakyi L. Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines. Ticks Tick Borne Dis. 2012;3:137–146. doi: 10.1016/j.ttbdis.2012.05.002. - DOI - PMC - PubMed
    1. Al-Khalifa MS, Diab FM, Khalil GM. Man-threatening viruses isolated from ticks in Saudi Arabia. Saudi Med J. 2007;28:1864–1867. - PubMed
    1. Al’khovskii SV, L’Vov DK, Shchelkanov M, Shchetinin AM, Deriabin PG, Samokhvalov EI, Gitel’man AK, Botikov AG. The taxonomy of the Khasan virus (KHAV), a new representative of phlebovirus genera (Bunyaviridae), isolated from the ticks haemaphysalis longicornis (Neumann, 1901) in the Maritime Territory (Russia) Vopr Virusol. 2013;58:15–18. - PubMed