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Case Reports
. 2018 Apr-Jun;17(2):86-89.
doi: 10.4103/aam.aam_30_17.

Longitudinally extensive transverse myelitis following dengue virus infection: A rare entity

Sunil Malik  1 , Sonal Saran  2 , Archana Dubey  1 , Ajay Punj  1
Affiliations
Case Reports

Longitudinally extensive transverse myelitis following dengue virus infection: A rare entity

Sunil Malik et al. Ann Afr Med. 2018 Apr-Jun.

Abstract
in English, French

Association of dengue fever with longitudinally extensive transverse myelitis in pediatric age group is a rare entity. We describe a case of 15 year old adolescent male who presented with dengue fever and in whom symptoms of transverse myelitis developed 4 weeks after fever (post-infectious stage). Magnetic resonance imaging confirmed the diagnosis of longitudinally extensive transverse myelitis involving dorso-lumbar cord. Patient recovered almost completely with minimal residual neurological deficit after a six weeks course of corticosteroids and supportive management including physiotherapy.

L'association de la dengue avec une myélite transversale longitudinale étendue dans un groupe d'âge pédiatrique est une entité rare. Nous décrivons un cas d'un adolescent de 15 ans qui présentaient une dengue et chez lesquels des symptômes de myélite transversale se sont développés 4 semaines après la fièvre (stade post-infectieux). L'imagerie par résonance magnétique a confirmé le diagnostic de myélite transversale longitudinale étendue impliquant le cordon dorso-lombaire. Le patient s'est rétabli presque complètement avec un déficit neurologique résiduel minimal après un traitement de corticostéroïdes de six semaines et une prise en charge, y compris la physiothérapie. Mots-clés: La fièvre de la dengue, la myélite transversale longitudinalement étendue, le virus neurotroptique.

Keywords: Dengue fever; longitudinally extensive transverse myelitis; neurotropic virus.

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Conflict of interest statement

There are no conflicts of interest

Figures

Figure 1
Figure 1
(a and b) Sagittal T2-weighted sequences covering cervical, dorsal, and lumbar cords showing continuous intramedullary T2 hyperintense signal intensity in the long segment of the dorsal and lumbar cords extending from T5 to the conus medullaris. (c) Axial T2-weighted sequences at the level of D5–D6 showing similar intramedullary T2 hyperintense signal intensity, mainly involving the central region of the cord. (d) Axial T2-weighted sequences at the level of D10 showing similar intramedullary T2 hyperintense signal intensity, mainly involving the central region of the cord. (e) Magnetic resonance myelography covering dorsolumbar region showing continuous intramedullary hyperintense signal intensity in the long segment of the dorsal and lumbar cords
Figure 2
Figure 2
Categorization of neurological features of dengue by Carod-Artal et al
Figure 3
Figure 3
Categorization of neurological features of dengue by Murthy
See this image and copyright information in PMC

References

    1. Chaudhuri M. What can India do about dengue fever? BMJ. 2013;346:f643. - PubMed
    1. World Health Organization. Dengue: Guidelines for Diagnosis, Treatment, Prevention, and Control. New edition. Geneva: TDR/World Health Organization; 2009. - PubMed
    1. Hendarto SK, Hadinegoro SR. Dengue encephalopathy. Acta Paediatr Jpn. 1992;34:350–7. - PubMed
    1. Solomon T, Dung NM, Vaughn DW, Kneen R, Thao LT, Raengsakulrach B, et al. Neurological manifestations of dengue infection. Lancet. 2000;355:1053–9. - PubMed
    1. Carod-Artal FJ, Wichmann O, Farrar J, Gascón J. Neurological complications of dengue virus infection. Lancet Neurol. 2013;12:906–19. - PubMed

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