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Randomized Controlled Trial
. 2018 Mar 14:24:1524-1532.
doi: 10.12659/msm.907284.

WeChat Public Account Use Improves Clinical Control of Cough-Variant Asthma: A Randomized Controlled Trial

Yuan Cao  1 , Shi-Hua Lin  1 , Ding Zhu  1 , Feng Xu  1 , Zhi-Hua Chen  1 , Hua-Hao Shen  1 , Wen Li  1
Affiliations
Randomized Controlled Trial

WeChat Public Account Use Improves Clinical Control of Cough-Variant Asthma: A Randomized Controlled Trial

Yuan Cao et al. Med Sci Monit. .

Abstract

BACKGROUND WeChat is a convenient and popular social medium, and it seems to be an appropriate platform for education and management of patients. This study sought to identify usefulness in clinical control of cough-variant asthma (CVA). MATERIAL AND METHODS A randomized controlled trial was conducted among 80 CVA patients. After being assigned to either the traditional group (TG) or the WeChat group (WG), they received the same inhalation therapy, but patients in WG received additional education and instruction via our public account on the WeChat application. Questionnaires on asthma and chronic cough, data on pulmonary function, blood-related items, follow-up adherence, and Emergency Department (ED) visits were collected at the initial visit and at 3 months. RESULTS A total of 67 participants completed the trial for analysis. FEV1/predicted and FEV1/FVC were significantly increased in WG (p<0.001; p=0.012) after 3 months. PD20-FEV1 was increased in both groups compared with baseline, but more pronounced in WG (p=0.004). ACQ-7 scores were improved in both groups (p=0.024; p<0.001). Participants allocated to WG experienced a greater improvement in AQLQ and LCQ scores, and between-group differences were significant at 3 months (p=0.040; p=0.001). Furthermore, we observed decreases in blood eosinophil count and FeNO in WG (p=0.048; p=0.014), and WG presented better follow-up compliance (p=0.034). CONCLUSIONS Using WeChat as part of treatment and management of CVA can help patients learn about their disease and medications, as well as improve disease control and therapy outcomes.

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Conflict of interest statement

Conflict of interest

None.

Figures

Figure 1
Figure 1
Flow of participants through the study.
Figure 2
Figure 2
Change of PD20-FEV1 in 2 groups.
Figure 3
Figure 3
Effects of WeChat intervention on (A): LCQ; (B) Social, psychological and physiological scores of LCQ.
Figure 4
Figure 4
Follow-up adherence and ED visits (or hospitalization) in 2 groups.
See this image and copyright information in PMC

References

    1. Pratter MR. Overview of common causes of chronic cough: ACCP evidence-based clinical practice guidelines. Chest. 2006;129:59S–62S. - PubMed
    1. Saito N, Itoga M, Tamaki M, et al. Cough variant asthma patients are more depressed and anxious than classic asthma patients. J Psychosom Res. 2015;79:18–26. - PubMed
    1. Dicpinigaitis PV. Chronic cough due to asthma: ACCP evidence-based clinical practice guidelines. Chest. 2006;129:75S–79S. - PubMed
    1. Kohno S, Ishida T, Uchida Y, et al. The Japanese Respiratory Society guidelines for management of cough. Respirology. 2006;11(Suppl 4):S135–86. - PubMed
    1. Zapata BC, Fernandez-Aleman JL, Idri A, Toval A. Empirical studies on usability of mHealth apps: A systematic literature review. J Med Syst. 2015;39:1. - PubMed

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