The value of including thalamic atrophy as a clinical trial endpoint in multiple sclerosis

Affiliations

¹ From the Department of Anatomy and Neurosciences (M.M.S.), Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, the Netherlands; Department of Neuroinflammation (O.C.), UCL Institute of Neurology, University College London; and National Institute for Health Research (O.C.), University College London Hospitals Biomedical Research Centre, UK. m.schoonheim@vumc.nl.
² From the Department of Anatomy and Neurosciences (M.M.S.), Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, the Netherlands; Department of Neuroinflammation (O.C.), UCL Institute of Neurology, University College London; and National Institute for Health Research (O.C.), University College London Hospitals Biomedical Research Centre, UK.

Editorial

Menno M Schoonheim et al. Neurology. 2018.

. 2018 Apr 10;90(15):677-678.

doi: 10.1212/WNL.0000000000005279. Epub 2018 Mar 14.

¹ From the Department of Anatomy and Neurosciences (M.M.S.), Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, the Netherlands; Department of Neuroinflammation (O.C.), UCL Institute of Neurology, University College London; and National Institute for Health Research (O.C.), University College London Hospitals Biomedical Research Centre, UK. m.schoonheim@vumc.nl.
² From the Department of Anatomy and Neurosciences (M.M.S.), Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, the Netherlands; Department of Neuroinflammation (O.C.), UCL Institute of Neurology, University College London; and National Institute for Health Research (O.C.), University College London Hospitals Biomedical Research Centre, UK.

No abstract available

Comment on

Fingolimod effect on gray matter, thalamus, and white matter in patients with multiple sclerosis.
Gaetano L, Häring DA, Radue EW, Mueller-Lenke N, Thakur A, Tomic D, Kappos L, Sprenger T. Gaetano L, et al. Neurology. 2018 Apr 10;90(15):e1324-e1332. doi: 10.1212/WNL.0000000000005292. Epub 2018 Mar 14. Neurology. 2018. PMID: 29540589 Clinical Trial.