Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Mar 14;9(3):409.
doi: 10.1038/s41419-018-0455-7.

Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration

Affiliations
Comment

Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration

Jacqueline Larouche et al. Cell Death Dis. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1. Volumetric muscle loss (VML) is proposed to induce a barrier to muscle regeneration through a feedback loop driven from inflammation and fibrosis.
The activation of this feedback loop prevents the reparative activities of myogenic progenitors on multiple levels and prevents appropriate healing

Comment on

References

    1. Grogan BF, Hsu JR. J. Am. Acad. Orthop. Surg. 2011;19:S35–S37. doi: 10.5435/00124635-201102001-00007. - DOI - PubMed
    1. Corona BT, Wenke JC, Ward CL. Cells Tissues Organs. 2015;202:180–188. doi: 10.1159/000443925. - DOI - PubMed
    1. Quarta M, et al. Nat. Comm. 2017;8:15613. doi: 10.1038/ncomms15613. - DOI - PMC - PubMed
    1. Grasman JM, Zayas MJ, Page RL, Pins GD. Acta Biomater. 2015;25:2–15. doi: 10.1016/j.actbio.2015.07.038. - DOI - PMC - PubMed
    1. Aguilar CA, et al. Cell Death Discov. 2018;4:33. doi: 10.1038/s41420-018-0027-8. - DOI - PMC - PubMed

LinkOut - more resources