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Case Reports
. 2017 May-Aug;21(2):94-96.
doi: 10.4103/ijoem.IJOEM_120_17.

Erasmus Syndrome: Silicosis and Systemic Sclerosis

Shubhra Jain  1 , Vinod Joshi  1 , Yogendra S Rathore  1 , Narendra Khippal  1
Affiliations
Case Reports

Erasmus Syndrome: Silicosis and Systemic Sclerosis

Shubhra Jain et al. Indian J Occup Environ Med. 2017 May-Aug.

Abstract

Several occupational hazards, especially exposure to silica, have been implicated as causal factors for the development of scleroderma-like disorders. Compared to other connective tissue disorders, silica-associated systemic sclerosis (SA-SS) is relatively rare. Silica-induced scleroderma is indistinguishable from idiopathic systemic sclerosis. However, the former expresses a high predisposition of pulmonary involvement and anti-Scl-70 antibody. We report the case of a 42-year-old male, stone cutter by occupation, who was diagnosed as simple chronic silicosis and developed systemic sclerosis.

Keywords: Chronic silicosis; scleroderma; systemic sclerosis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Tight and shiny skin over the neck, arms, and chest
Figure 2
Figure 2
Pitted scar at finger tips on both hands
Figure 3
Figure 3
X-ray of the chest showing bilateral nodular opacity over the mid and lower lung zones
Figure 4
Figure 4
High-resolution computed tomography of the chest showing multiple randomly distributed nodules in both lungs
See this image and copyright information in PMC

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