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Case Reports
. 2018 Jan 28:17:97-99.
doi: 10.1016/j.eucr.2017.12.006. eCollection 2018 Mar.

Two cases of nonbacterial cystitis associated with nivolumab, the anti-programmed-death-receptor-1 inhibitor

Kimihiro Shimatani  1 , Tetsuro Yoshimoto  1 , Yutaka Doi  1 , Takashi Sonoda  2 , Shingo Yamamoto  3 , Akihiro Kanematsu  3
Affiliations
Case Reports

Two cases of nonbacterial cystitis associated with nivolumab, the anti-programmed-death-receptor-1 inhibitor

Kimihiro Shimatani et al. Urol Case Rep. .
No abstract available

Keywords: Cystitis; Nivolumab; PD-1.

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Figures

Fig. 1
Fig. 1
A). Clinical course of Case 1. B) Cytological appearance of urine in Case 1. Acute inflammation mainly consisted of neutrophils in urine cytology.
Fig. 2
Fig. 2
A). Clinical course of Case 2. B) Cytological appearance of urine in Case 2. Inflammatory cells consisted of neutrophils and lymphocytes in urine cytology.
See this image and copyright information in PMC

References

    1. Larkin J., Chiarion-Sileni V., Gonzalez R. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med. 2015;373:23–34. - PMC - PubMed
    1. ONO Pharmaceutical Opdivo (Nivolumab) Guide for Appropriate Use (NSCLC) https://uat.opdivo.jp/contents/pdf/open/guide_nsclc.pdf
    1. ONO Pharmaceutical Opdivo (Nivolumab) Occurrence of Adverse Drug Reactions. https://uat.opdivo.jp/contents/pdf/open/side_effect.pdf
    1. Sugino Y., Nishikawa N., Yoshimura K. BALB/c-Fcgr2bPdcd1 mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis. Sci Rep. 2012;2:317. - PMC - PubMed
    1. Katharina C.K., Jessica C.H., Lucie H. Management of side effects of immune checkpoint blockade by anti-CTLA-4 and anti-PD-1 antibodies in metastatic melanoma. JDDG. 2016;14(7):662–681. - PubMed

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