Review
doi: 10.1002/hed.25140.
Epub 2018 Mar 15.
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Affiliations
- PMID: 29542214
- DOI: 10.1002/hed.25140
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Review
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Head Neck.
2018 Jul.
Abstract
The use of circulating biochemical molecular markers in head and neck cancer holds the promise of improved diagnostics, treatment planning, and posttreatment surveillance. In this review, we provide an introduction for the head and neck surgeon of the basic science, current evidence, and future applications of circulating tumor DNA (ctDNA) as a biomarker and liquid biopsy to detect tumor genetic heterogeneity in patients with head and neck squamous cell carcinoma (HNSCC).
Keywords: biomarker; circulating tumor DNA (ctDNA); head and neck cancer; liquid biopsy.
© 2018 The Authors Head & Neck Published by Wiley Periodicals, Inc.
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