Noncoding Genetic Variation and Gene Expression: Deciphering the Molecular Drivers of Genome-Wide Association Study Signals in Atrial Fibrillation

Affiliations

¹ From the Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Western University, London, ON, Canada. jason.roberts@lhsc.on.ca.

Editorial

Jason D Roberts. Circ Genom Precis Med. 2018 Mar.

. 2018 Mar;11(3):e002109.

doi: 10.1161/CIRCGEN.118.002109.

¹ From the Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Western University, London, ON, Canada. jason.roberts@lhsc.on.ca.

No abstract available

Keywords: Editorials; atrial appendage; atrial fibrillation; gene expression; genetics; quantitative trait loci.

Comment on

Genetic Control of Left Atrial Gene Expression Yields Insights into the Genetic Susceptibility for Atrial Fibrillation.
Hsu J, Gore-Panter S, Tchou G, Castel L, Lovano B, Moravec CS, Pettersson GB, Roselli EE, Gillinov AM, McCurry KR, Smedira NG, Barnard J, Van Wagoner DR, Chung MK, Smith JD. Hsu J, et al. Circ Genom Precis Med. 2018 Mar;11(3):e002107. doi: 10.1161/CIRCGEN.118.002107. Circ Genom Precis Med. 2018. PMID: 29545482 Free PMC article.

Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis.
Laforest B, Dai W, Tyan L, Lazarevic S, Shen KM, Gadek M, Broman MT, Weber CR, Moskowitz IP. Laforest B, et al. J Clin Invest. 2019 Nov 1;129(11):4937-4950. doi: 10.1172/JCI124231. J Clin Invest. 2019. PMID: 31609246 Free PMC article.