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. 2018 Apr 1;22(2):157-168.
doi: 10.1188/18.CJON.157-168.

Prevention of Infection: A Systematic Review of Evidence-Based Practice Interventions for Management in Patients With Cancer

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Prevention of Infection: A Systematic Review of Evidence-Based Practice Interventions for Management in Patients With Cancer

Barbara J Wilson et al. Clin J Oncol Nurs. .

Abstract

Background: Cancer-related infections lead to increases in mortality, antibiotic use, and hospital stays. Other adverse outcomes include dose delays and reductions, which can result in suboptimal treatment outcomes.

Objectives: Effective implementation of risk assessment and evidence-based interventions for the prevention and treatment of infection are essential to improve care and reduce costs related to infections in patients with cancer receiving immunosuppressive therapy.

Methods: The Oncology Nursing Society (ONS) Putting Evidence Into Practice (PEP) prevention of infection resource have been developed and updated to identify and disseminate the best available scientific evidence.

Findings: Pharmacologic and nonpharmacologic interventions were evaluated, resulting in recommended for practice rating for catheter care bundles, antimicrobial prophylaxis, vaccination for specific populations, and implementation of contact precautions for resistant organisms.

Keywords: PEP; cancer-related infection; evidence-based practice; prevention of infection.

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