Published Erratum
doi: 10.1038/s41588-018-0050-y.
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Valérie Turcot #
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; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetic Consortium; GoT2D Genes Consortium; EPIC InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; MAGIC Investigators; Understanding Society Scientific Group
Affiliations
Affiliations
- 1 Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
- 2 Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
- 3 Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 4 Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 5 Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
- 6 Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 7 Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 8 Department of Genetics, Harvard Medical School, Boston, MA, USA.
- 9 Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
- 10 Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
- 11 Quantinuum Research, LLC, San Diego, CA, USA.
- 12 Estonian Genome Center, University of Tartu, Tartu, Estonia.
- 13 Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
- 14 Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
- 15 Wellcome Trust Sanger Institute, Hinxton, UK.
- 16 Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA.
- 17 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
- 18 Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus.
- 19 Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
- 20 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
- 21 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.
- 22 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- 23 Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.
- 24 Massachusetts General Hospital, Boston, MA, USA.
- 25 Department of Haematology, University of Cambridge, Cambridge, UK.
- 26 Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
- 27 Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.
- 28 NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
- 29 Department of Medicine, Harvard Medical School, Boston, MA, USA.
- 30 Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA.
- 31 Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 32 Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
- 33 Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 34 Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 35 Department of Epidemiology, University of Washington, Seattle, WA, USA.
- 36 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- 37 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK.
- 38 Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
- 39 Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
- 40 Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
- 41 School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada.
- 42 Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
- 43 Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.
- 44 INSERM U1167, Lille, France.
- 45 Institut Pasteur de Lille, U1167, Lille, France.
- 46 Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
- 47 Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
- 48 Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.
- 49 Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
- 50 Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
- 51 INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France.
- 52 Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 53 Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
- 54 NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
- 55 Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
- 56 Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
- 57 Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 58 Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
- 59 Swiss Institute of Bioinformatics, Lausanne, Switzerland.
- 60 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
- 61 IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.
- 62 Department of Medicine, University of Leipzig, Leipzig, Germany.
- 63 Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.
- 64 School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 65 Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
- 66 Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
- 67 Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 68 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
- 69 Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 70 Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.
- 71 Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
- 72 MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
- 73 NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
- 74 Marshfield Clinic Research Institute, Marshfield, WI, USA.
- 75 Department of Medical Sciences, University of Trieste, Trieste, Italy.
- 76 Department of Medicine, University of Washington, Seattle, WA, USA.
- 77 MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 78 NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 79 Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA.
- 80 Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
- 81 Weis Center for Research, Geisinger Health System, Danville, PA, USA.
- 82 NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- 83 Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.
- 84 Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
- 85 Imperial College Healthcare NHS Trust, London, UK.
- 86 Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 87 Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 88 Harvard Medical School, Boston, MA, USA.
- 89 Medical Department, Lillebaelt Hospital, Vejle, Denmark.
- 90 NHLBI Framingham Heart Study, Framingham, MA, USA.
- 91 Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA.
- 92 Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
- 93 Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA.
- 94 Department of Biostatistics, University of Liverpool, Liverpool, UK.
- 95 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
- 96 Department of Psychology, University of Edinburgh, Edinburgh, UK.
- 97 Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
- 98 Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
- 99 Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.
- 100 Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA.
- 101 Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
- 102 QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
- 103 British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK.
- 104 Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
- 105 Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.
- 106 Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
- 107 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
- 108 Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
- 109 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
- 110 Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
- 111 Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
- 112 Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 113 Institute of Cardiovascular Science, University College London, London, UK.
- 114 MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
- 115 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
- 116 Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
- 117 Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
- 118 Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
- 119 Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
- 120 Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
- 121 Department of Health Sciences, University of Leicester, Leicester, UK.
- 122 Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
- 123 Department of Ophthalmology, University of Cologne, Cologne, Germany.
- 124 CNR Institute of Clinical Physiology, Pisa, Italy.
- 125 Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
- 126 Toulouse University School of Medicine, Toulouse, France.
- 127 University of Glasgow, Glasgow, UK.
- 128 Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 129 Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.
- 130 Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
- 131 Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden.
- 132 Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
- 133 Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 134 Research Unit, AREA Science Park, Trieste, Italy.
- 135 Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK.
- 136 Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden.
- 137 Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.
- 138 Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
- 139 Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
- 140 German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany.
- 141 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
- 142 Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
- 143 Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK.
- 144 Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
- 145 Icelandic Heart Association, Kopavogur, Iceland.
- 146 Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
- 147 Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands.
- 148 Department of Sociology, University of North Carolina, Chapel Hill, NC, USA.
- 149 Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA.
- 150 University of Exeter Medical School, University of Exeter, Exeter, UK.
- 151 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
- 152 Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.
- 153 Department of Public Health, University of Helsinki, Helsinki, Finland.
- 154 Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
- 155 Department of Psychiatry, Washington University, St. Louis, MO, USA.
- 156 Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 157 Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
- 158 KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
- 159 Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 160 Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
- 161 Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 162 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.
- 163 Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.
- 164 Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia.
- 165 KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
- 166 Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China.
- 167 Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 168 Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 169 Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
- 170 Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
- 171 Research Unit Skellefteå, Skellefteå, Sweden.
- 172 Department of Genome Sciences, University of Washington, Seattle, WA, USA.
- 173 Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark.
- 174 Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
- 175 National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
- 176 Steno Diabetes Center Copenhagen, Gentofte, Denmark.
- 177 Faculty of Medicine, Aalborg University, Aalborg, Denmark.
- 178 Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.
- 179 Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
- 180 Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.
- 181 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
- 182 Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
- 183 Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.
- 184 Centre for Brain Research, Indian Institute of Science, Bangalore, India.
- 185 Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
- 186 Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 187 Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.
- 188 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
- 189 National Institute for Health and Welfare, Helsinki, Finland.
- 190 Echinos Medical Centre, Echinos, Greece.
- 191 Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 192 Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.
- 193 UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK.
- 194 Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
- 195 Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.
- 196 Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
- 197 National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.
- 198 MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
- 199 Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
- 200 Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
- 201 Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
- 202 Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.
- 203 Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
- 204 Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
- 205 Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
- 206 Department of Health Services, University of Washington, Seattle, WA, USA.
- 207 Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.
- 208 USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines.
- 209 Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
- 210 Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
- 211 Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.
- 212 Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
- 213 Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.
- 214 Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 215 Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
- 216 Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA.
- 217 Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 218 Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
- 219 Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
- 220 Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.
- 221 German Center for Diabetes Research, Neuherberg, Germany.
- 222 Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia.
- 223 Department of Medicine, Kuopio University Hospital, Kuopio, Finland.
- 224 Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.
- 225 Department of Public Health, University Hospital of Strasbourg, Strasbourg, France.
- 226 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
- 227 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
- 228 INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 229 School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.
- 230 Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
- 231 Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.
- 232 German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
- 233 Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.
- 234 Data Tecnica International, Glen Echo, MD, USA.
- 235 Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
- 236 Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
- 237 Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 238 Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
- 239 Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK.
- 240 Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.
- 241 School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia.
- 242 Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland.
- 243 Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
- 244 Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 245 Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark.
- 246 School of Medicine, University of Split, Split, Croatia.
- 247 Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland.
- 248 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
- 249 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
- 250 Centre for Non-Communicable Diseases, Karachi, Pakistan.
- 251 Department of Biobank Research, Umeå University, Umeå, Sweden.
- 252 Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
- 253 NHS Blood and Transplant-Oxford Centre, Oxford, UK.
- 254 BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 255 Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden.
- 256 Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
- 257 Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
- 258 Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
- 259 Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
- 260 Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
- 261 School of Medicine, National Defense Medical Center, Taipei, Taiwan.
- 262 School of Medicine, National Yang-Ming University, Taipei, Taiwan.
- 263 Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore.
- 264 Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.
- 265 OmicSoft at Qiagen Company, Cary, NC, USA.
- 266 Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
- 267 Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
- 268 deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
- 269 Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.
- 270 Kanazawa University, Kanazawa, Japan.
- 271 College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
- 272 Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
- 273 Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany.
- 274 Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
- 275 Anogia Medical Centre, Anogia, Greece.
- 276 Centre for Vascular Prevention, Danube University Krems, Krems, Austria.
- 277 Dasman Diabetes Institute, Dasman, Kuwait.
- 278 Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
- 279 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
- 280 Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
- 281 Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
- 282 Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
- 283 Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.
- 284 Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
- 285 USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
- 286 Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
- 287 Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
- 288 Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA.
- 289 German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.
- 290 Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
- 291 Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK.
- 292 Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
- 293 Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA.
- 294 Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA.
- 295 Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand.
- 296 Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
- 297 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.
- 298 Danish Diabetes Academy, Odense, Denmark.
- 299 Department of Public Health, Aarhus University, Aarhus, Denmark.
- 300 GlaxoSmithKline, King of Prussia, PA, USA.
- 301 Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA.
- 302 Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK.
- 303 Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA.
- 304 Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK.
- 305 Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.
- 306 Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.
- 307 Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.
- 308 Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.
- 309 Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
- 310 Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
- 311 Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
# Contributed equally.
- PMID: 29549329
- DOI: 10.1038/s41588-018-0050-y
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Published Erratum
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Valérie Turcot et al.
Nat Genet.
2018 May.
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doi: 10.1038/s41588-018-0050-y.
Authors
Valérie Turcot #
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, Yingchang Lu #
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, Heather M Highland #
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, Claudia Schurmann #
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, Anne E Justice #
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, Rebecca S Fine #
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, Jonathan P Bradfield
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, Tõnu Esko
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, Ayush Giri
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, Mariaelisa Graff
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, Xiuqing Guo
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, Audrey E Hendricks
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, Tugce Karaderi
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, Adelheid Lempradl
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, Adam E Locke
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, Anubha Mahajan
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, Eirini Marouli
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, Suthesh Sivapalaratnam
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, Kristin L Young
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, Tamuno Alfred
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, Mary F Feitosa
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, Nicholas G D Masca
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, Alisa K Manning
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, Carolina Medina-Gomez
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, Poorva Mudgal
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, Maggie C Y Ng
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, Alex P Reiner
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, Sailaja Vedantam
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, Sara M Willems
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, Thomas W Winkler
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, Gonçalo Abecasis
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, Katja K Aben
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, Dewan S Alam
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, Sameer E Alharthi
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, Matthew Allison
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, Philippe Amouyel
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, Folkert W Asselbergs
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, Paul L Auer
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, Beverley Balkau
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, Lia E Bang
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, Inês Barroso
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, Lisa Bastarache
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, Marianne Benn
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, Sven Bergmann
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, Lawrence F Bielak
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, Matthias Blüher
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, Michael Boehnke
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, Heiner Boeing
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, Eric Boerwinkle
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, Carsten A Böger
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, Jette Bork-Jensen
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, Michiel L Bots
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, Erwin P Bottinger
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, Donald W Bowden
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, Ivan Brandslund
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, Gerome Breen
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, Murray H Brilliant
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, Linda Broer
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, Marco Brumat
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, Amber A Burt
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, Adam S Butterworth
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, Peter T Campbell
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, Stefania Cappellani
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, David J Carey
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, Eulalia Catamo
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, Mark J Caulfield
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, John C Chambers
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, Daniel I Chasman
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, Yii-Der I Chen
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, Rajiv Chowdhury
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, Cramer Christensen
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, Audrey Y Chu
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, Massimiliano Cocca
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, Francis S Collins
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, James P Cook
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, Janie Corley
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, Jordi Corominas Galbany
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, Amanda J Cox
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, David S Crosslin
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, Gabriel Cuellar-Partida
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, Angela D'Eustacchio
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, John Danesh
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, Gail Davies
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, Paul I W Bakker
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, Mark C H Groot
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, Renée Mutsert
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, Ian J Deary
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, George Dedoussis
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, Ellen W Demerath
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, Martin Heijer
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, Anneke I Hollander
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, Hester M Ruijter
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, Joe G Dennis
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, Josh C Denny
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, Emanuele Angelantonio
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, Fotios Drenos
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, Mengmeng Du
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, Marie-Pierre Dubé
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, Alison M Dunning
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, Douglas F Easton
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, Todd L Edwards
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, David Ellinghaus
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, Patrick T Ellinor
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, Paul Elliott
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, Evangelos Evangelou
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, Aliki-Eleni Farmaki
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, I Sadaf Farooqi
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, Jessica D Faul
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, Sascha Fauser
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, Shuang Feng
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, Ele Ferrannini
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, Jean Ferrieres
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, Jose C Florez
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, Ian Ford
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, Myriam Fornage
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, Oscar H Franco
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, Andre Franke
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, Paul W Franks
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, Nele Friedrich
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, Ruth Frikke-Schmidt
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, Tessel E Galesloot
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, Wei Gan
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, Ilaria Gandin
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, Paolo Gasparini
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, Jane Gibson
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, Vilmantas Giedraitis
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, Anette P Gjesing
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, Penny Gordon-Larsen
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, Mathias Gorski
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, Hans-Jörgen Grabe
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, Struan F A Grant
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, Niels Grarup
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, Helen L Griffiths
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, Megan L Grove
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, Vilmundur Gudnason
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, Stefan Gustafsson
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, Jeff Haessler
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, Hakon Hakonarson
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, Anke R Hammerschlag
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, Torben Hansen
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, Kathleen Mullan Harris
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, Tamara B Harris
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, Andrew T Hattersley
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, Christian T Have
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, Caroline Hayward
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, Liang He
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, Nancy L Heard-Costa
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, Andrew C Heath
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, Iris M Heid
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, Øyvind Helgeland
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, Jussi Hernesniemi
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, Alex W Hewitt
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, Oddgeir L Holmen
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, G Kees Hovingh
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, Joanna M M Howson
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, Yao Hu
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, Paul L Huang
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, Jennifer E Huffman
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, M Arfan Ikram
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, Erik Ingelsson
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, Anne U Jackson
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, Jan-Håkan Jansson
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, Gail P Jarvik
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, Gorm B Jensen
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, Yucheng Jia
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, Stefan Johansson
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, Marit E Jørgensen
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, Torben Jørgensen
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, René S Kahn
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, Sharon L R Kardia
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, Fredrik Karpe
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, Sekar Kathiresan
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, Frank Kee
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, Lambertus A Kiemeney
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, Eric Kim
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, Hidetoshi Kitajima
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, Markku Laakso
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, Leslie A Lange
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, Claudia Langenberg
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, Eric B Larson
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, Cora E Lewis
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, Huaixing Li
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, Jin Li
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, Ruifang Li-Gao
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, Honghuang Lin
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, Keng-Hung Lin
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, Li-An Lin
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, Xu Lin
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, Lars Lind
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, Jaana Lindström
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, Allan Linneberg
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, Dajiang J Liu
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, Yongmei Liu
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, Ken S Lo
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, Andrew J Lotery
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, Gaëlle Marenne
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, Chris J Packard
127
, Sandosh Padmanabhan
127
, Colin N A Palmer
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, Nicholette D Palmer
69
, Gerard Pasterkamp
111
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, Aniruddh P Patel
7
24
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, Alison Pattie
96
, Oluf Pedersen
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, Peggy L Peissig
74
, Gina M Peloso
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, Craig E Pennell
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, Markus Perola
12
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, James A Perry
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, John R B Perry
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, Tune H Pers
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, Thomas N Person
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, Annette Peters
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, Eva R B Petersen
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, Patricia A Peyser
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, Ailith Pirie
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, Ozren Polasek
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, Tinca J Polderman
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, Hannu Puolijoki
247
, Olli T Raitakari
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, Asif Rasheed
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, Rainer Rauramaa
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, Dermot F Reilly
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, Frida Renström
129
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, Myriam Rheinberger
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, Paul M Ridker
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, John D Rioux
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, Manuel A Rivas
7
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, David J Roberts
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, Neil R Robertson
17
191
, Antonietta Robino
80
, Olov Rolandsson
170
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, Igor Rudan
230
, Katherine S Ruth
256
, Danish Saleheen
250
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, Veikko Salomaa
189
, Nilesh J Samani
27
28
, Yadav Sapkota
102
, Naveed Sattar
127
, Robert E Schoen
258
, Pamela J Schreiner
109
, Matthias B Schulze
220
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, Robert A Scott
37
, Marcelo P Segura-Lepe
84
, Svati H Shah
259
, Wayne H-H Sheu
260
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, Xueling Sim
20
263
, Andrew J Slater
264
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, Kerrin S Small
266
, Albert V Smith
144
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, Lorraine Southam
15
17
, Timothy D Spector
266
, Elizabeth K Speliotes
181
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, John M Starr
95
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, Kari Stefansson
144
268
, Valgerdur Steinthorsdottir
268
, Kathleen E Stirrups
22
25
, Konstantin Strauch
156
269
, Heather M Stringham
20
, Michael Stumvoll
61
62
, Liang Sun
152
153
, Praveen Surendran
77
, Amy J Swift
93
, Hayato Tada
237
270
, Katherine E Tansey
114
271
, Jean-Claude Tardif
1
, Kent D Taylor
14
, Alexander Teumer
272
, Deborah J Thompson
112
, Gudmar Thorleifsson
268
, Unnur Thorsteinsdottir
144
268
, Betina H Thuesen
178
, Anke Tönjes
273
, Gerard Tromp
81
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, Stella Trompet
179
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, Emmanouil Tsafantakis
275
, Jaakko Tuomilehto
189
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, Anne Tybjaerg-Hansen
57
133
, Jonathan P Tyrer
117
, Rudolf Uher
279
, André G Uitterlinden
31
32
, Matti Uusitupa
280
, Sander W Laan
111
, Cornelia M Duijn
31
, Nienke Leeuwen
281
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, Jessica van Setten
47
, Mauno Vanhala
283
284
, Anette Varbo
56
57
, Tibor V Varga
129
, Rohit Varma
285
, Digna R Velez Edwards
286
, Sita H Vermeulen
40
, Giovanni Veronesi
287
, Henrik Vestergaard
67
176
, Veronique Vitart
151
, Thomas F Vogt
288
, Uwe Völker
289
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, Dragana Vuckovic
75
80
, Lynne E Wagenknecht
217
, Mark Walker
291
, Lars Wallentin
292
, Feijie Wang
166
, Carol A Wang
241
, Shuai Wang
215
, Yiqin Wang
166
, Erin B Ware
60
122
, Nicholas J Wareham
37
, Helen R Warren
22
82
, Dawn M Waterworth
293
, Jennifer Wessel
294
, Harvey D White
295
, Cristen J Willer
181
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296
, James G Wilson
297
, Daniel R Witte
298
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, Andrew R Wood
256
, Ying Wu
204
, Hanieh Yaghootkar
256
, Jie Yao
14
, Pang Yao
166
, Laura M Yerges-Armstrong
236
300
, Robin Young
77
127
, Eleftheria Zeggini
15
, Xiaowei Zhan
301
, Weihua Zhang
83
84
, Jing Hua Zhao
37
, Wei Zhao
60
257
, Wei Zhou
181
182
, Krina T Zondervan
17
302
, Jerome I Rotter
14
, John A Pospisilik
19
, Fernando Rivadeneira
31
32
, Ingrid B Borecki
26
, Panos Deloukas
22
42
, Timothy M Frayling
256
, Guillaume Lettre
1
116
, Kari E North
303
, Cecilia M Lindgren
17
304
, Joel N Hirschhorn
305
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, Ruth J F Loos
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; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetic Consortium; GoT2D Genes Consortium; EPIC InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; MAGIC Investigators; Understanding Society Scientific Group
Affiliations
- 1 Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
- 2 Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
- 3 Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 4 Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- 5 Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
- 6 Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 7 Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 8 Department of Genetics, Harvard Medical School, Boston, MA, USA.
- 9 Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
- 10 Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
- 11 Quantinuum Research, LLC, San Diego, CA, USA.
- 12 Estonian Genome Center, University of Tartu, Tartu, Estonia.
- 13 Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
- 14 Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
- 15 Wellcome Trust Sanger Institute, Hinxton, UK.
- 16 Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA.
- 17 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
- 18 Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus.
- 19 Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
- 20 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
- 21 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.
- 22 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- 23 Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.
- 24 Massachusetts General Hospital, Boston, MA, USA.
- 25 Department of Haematology, University of Cambridge, Cambridge, UK.
- 26 Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
- 27 Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.
- 28 NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
- 29 Department of Medicine, Harvard Medical School, Boston, MA, USA.
- 30 Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA.
- 31 Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 32 Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
- 33 Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 34 Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 35 Department of Epidemiology, University of Washington, Seattle, WA, USA.
- 36 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
- 37 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK.
- 38 Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
- 39 Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
- 40 Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
- 41 School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada.
- 42 Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
- 43 Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.
- 44 INSERM U1167, Lille, France.
- 45 Institut Pasteur de Lille, U1167, Lille, France.
- 46 Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
- 47 Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
- 48 Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.
- 49 Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
- 50 Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
- 51 INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France.
- 52 Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 53 Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
- 54 NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
- 55 Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
- 56 Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
- 57 Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 58 Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
- 59 Swiss Institute of Bioinformatics, Lausanne, Switzerland.
- 60 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
- 61 IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.
- 62 Department of Medicine, University of Leipzig, Leipzig, Germany.
- 63 Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.
- 64 School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 65 Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
- 66 Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
- 67 Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 68 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
- 69 Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 70 Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.
- 71 Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
- 72 MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
- 73 NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK.
- 74 Marshfield Clinic Research Institute, Marshfield, WI, USA.
- 75 Department of Medical Sciences, University of Trieste, Trieste, Italy.
- 76 Department of Medicine, University of Washington, Seattle, WA, USA.
- 77 MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 78 NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 79 Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA.
- 80 Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
- 81 Weis Center for Research, Geisinger Health System, Danville, PA, USA.
- 82 NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
- 83 Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.
- 84 Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
- 85 Imperial College Healthcare NHS Trust, London, UK.
- 86 Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 87 Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 88 Harvard Medical School, Boston, MA, USA.
- 89 Medical Department, Lillebaelt Hospital, Vejle, Denmark.
- 90 NHLBI Framingham Heart Study, Framingham, MA, USA.
- 91 Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA.
- 92 Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
- 93 Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA.
- 94 Department of Biostatistics, University of Liverpool, Liverpool, UK.
- 95 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
- 96 Department of Psychology, University of Edinburgh, Edinburgh, UK.
- 97 Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
- 98 Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
- 99 Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.
- 100 Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA.
- 101 Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
- 102 QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
- 103 British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK.
- 104 Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
- 105 Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.
- 106 Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
- 107 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
- 108 Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
- 109 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
- 110 Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
- 111 Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
- 112 Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 113 Institute of Cardiovascular Science, University College London, London, UK.
- 114 MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
- 115 Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
- 116 Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
- 117 Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
- 118 Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
- 119 Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
- 120 Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
- 121 Department of Health Sciences, University of Leicester, Leicester, UK.
- 122 Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
- 123 Department of Ophthalmology, University of Cologne, Cologne, Germany.
- 124 CNR Institute of Clinical Physiology, Pisa, Italy.
- 125 Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
- 126 Toulouse University School of Medicine, Toulouse, France.
- 127 University of Glasgow, Glasgow, UK.
- 128 Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 129 Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.
- 130 Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
- 131 Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden.
- 132 Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
- 133 Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 134 Research Unit, AREA Science Park, Trieste, Italy.
- 135 Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK.
- 136 Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden.
- 137 Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.
- 138 Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
- 139 Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
- 140 German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany.
- 141 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
- 142 Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
- 143 Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK.
- 144 Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
- 145 Icelandic Heart Association, Kopavogur, Iceland.
- 146 Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
- 147 Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands.
- 148 Department of Sociology, University of North Carolina, Chapel Hill, NC, USA.
- 149 Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA.
- 150 University of Exeter Medical School, University of Exeter, Exeter, UK.
- 151 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
- 152 Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.
- 153 Department of Public Health, University of Helsinki, Helsinki, Finland.
- 154 Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
- 155 Department of Psychiatry, Washington University, St. Louis, MO, USA.
- 156 Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 157 Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
- 158 KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
- 159 Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 160 Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
- 161 Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 162 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.
- 163 Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.
- 164 Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia.
- 165 KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
- 166 Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China.
- 167 Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 168 Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.
- 169 Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
- 170 Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
- 171 Research Unit Skellefteå, Skellefteå, Sweden.
- 172 Department of Genome Sciences, University of Washington, Seattle, WA, USA.
- 173 Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark.
- 174 Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
- 175 National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
- 176 Steno Diabetes Center Copenhagen, Gentofte, Denmark.
- 177 Faculty of Medicine, Aalborg University, Aalborg, Denmark.
- 178 Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.
- 179 Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
- 180 Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.
- 181 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
- 182 Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
- 183 Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.
- 184 Centre for Brain Research, Indian Institute of Science, Bangalore, India.
- 185 Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
- 186 Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
- 187 Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.
- 188 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
- 189 National Institute for Health and Welfare, Helsinki, Finland.
- 190 Echinos Medical Centre, Echinos, Greece.
- 191 Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 192 Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.
- 193 UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK.
- 194 Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
- 195 Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.
- 196 Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
- 197 National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.
- 198 MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
- 199 Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
- 200 Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
- 201 Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
- 202 Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.
- 203 Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
- 204 Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
- 205 Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
- 206 Department of Health Services, University of Washington, Seattle, WA, USA.
- 207 Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.
- 208 USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines.
- 209 Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
- 210 Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
- 211 Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.
- 212 Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
- 213 Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.
- 214 Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 215 Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
- 216 Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA.
- 217 Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
- 218 Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
- 219 Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
- 220 Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.
- 221 German Center for Diabetes Research, Neuherberg, Germany.
- 222 Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia.
- 223 Department of Medicine, Kuopio University Hospital, Kuopio, Finland.
- 224 Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.
- 225 Department of Public Health, University Hospital of Strasbourg, Strasbourg, France.
- 226 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
- 227 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
- 228 INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
- 229 School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.
- 230 Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
- 231 Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.
- 232 German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
- 233 Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.
- 234 Data Tecnica International, Glen Echo, MD, USA.
- 235 Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
- 236 Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
- 237 Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
- 238 Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
- 239 Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK.
- 240 Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.
- 241 School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia.
- 242 Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland.
- 243 Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
- 244 Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 245 Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark.
- 246 School of Medicine, University of Split, Split, Croatia.
- 247 Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland.
- 248 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
- 249 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
- 250 Centre for Non-Communicable Diseases, Karachi, Pakistan.
- 251 Department of Biobank Research, Umeå University, Umeå, Sweden.
- 252 Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
- 253 NHS Blood and Transplant-Oxford Centre, Oxford, UK.
- 254 BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
- 255 Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden.
- 256 Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
- 257 Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
- 258 Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
- 259 Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
- 260 Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
- 261 School of Medicine, National Defense Medical Center, Taipei, Taiwan.
- 262 School of Medicine, National Yang-Ming University, Taipei, Taiwan.
- 263 Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore.
- 264 Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.
- 265 OmicSoft at Qiagen Company, Cary, NC, USA.
- 266 Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
- 267 Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
- 268 deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
- 269 Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.
- 270 Kanazawa University, Kanazawa, Japan.
- 271 College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
- 272 Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
- 273 Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany.
- 274 Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
- 275 Anogia Medical Centre, Anogia, Greece.
- 276 Centre for Vascular Prevention, Danube University Krems, Krems, Austria.
- 277 Dasman Diabetes Institute, Dasman, Kuwait.
- 278 Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
- 279 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
- 280 Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
- 281 Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
- 282 Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
- 283 Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.
- 284 Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.
- 285 USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
- 286 Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
- 287 Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
- 288 Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA.
- 289 German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.
- 290 Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
- 291 Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK.
- 292 Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
- 293 Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA.
- 294 Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA.
- 295 Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand.
- 296 Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
- 297 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.
- 298 Danish Diabetes Academy, Odense, Denmark.
- 299 Department of Public Health, Aarhus University, Aarhus, Denmark.
- 300 GlaxoSmithKline, King of Prussia, PA, USA.
- 301 Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA.
- 302 Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK.
- 303 Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA.
- 304 Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK.
- 305 Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.
- 306 Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.
- 307 Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.
- 308 Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.
- 309 Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
- 310 Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
- 311 Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
# Contributed equally.
- PMID: 29549329
- DOI: 10.1038/s41588-018-0050-y
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In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Di Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evange… See abstract for full author list ➔ Turcot V, et al. Nat Genet. 2018 Jan;50(1):26-41. doi: 10.1038/s41588-017-0011-x. Epub 2017 Dec 22. Nat Genet. 2018. PMID: 29273807 Free PMC article.
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