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. 2017 Dec 8:20:35-38.
doi: 10.1016/j.mmcr.2017.11.002. eCollection 2018 Jun.

Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina

Marcelo Label  1 , Luciana C Karayan  2 , Sybren De Hoog  3 , Javier Afeltra  2 , Togo Bustamante  1 , Roxana G Vitale  2   3   4
Affiliations

Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina

Marcelo Label et al. Med Mycol Case Rep. .

Abstract

Chromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to have been imported, but here we report the first endemic case by F. monophora from Argentina. Patient was a 82-year-old rural female worker from Corrientes, a province with a dry continental climate.

Keywords: Argentina; Chromoblastomycosis; Dematiaceous fungi; Fonsecaea monophora; South America.

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Figures

Fig. 1
Fig. 1
Muriform cells from the skin biopsy.
Fig. 2
Fig. 2
Microscopic examination from culture identified as Fonsecaea genera.
Fig. 3
Fig. 3
Lesions observed in the patient in different stages. A. First lesion from which F. monophora was isolated. B. Clinical improvement with imiquimol in the area of the previous lesion. However, a new lesion has appeared in the extreme area and the same fungus was isolated. C. Relapse of the lesion. D. Improvement of the lesion after itraconazole treatment.
See this image and copyright information in PMC

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