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. 2018 Mar 2:6:47.
doi: 10.3389/fpubh.2018.00047. eCollection 2018.

Effects of a Physical Exercise Program (PEP-Aut) on Autistic Children's Stereotyped Behavior, Metabolic and Physical Activity Profiles, Physical Fitness, and Health-Related Quality of Life: A Study Protocol

José Pedro Ferreira  1 , Chrystiane Vasconcelos Andrade Toscano  1   2 , Aristides Machado Rodrigues  3 , Guilherme Eustaquio Furtado  1 , Mauro Gomes Barros  4 , Rildo Souza Wanderley  4 , Humberto Moreira Carvalho  5
Affiliations

Effects of a Physical Exercise Program (PEP-Aut) on Autistic Children's Stereotyped Behavior, Metabolic and Physical Activity Profiles, Physical Fitness, and Health-Related Quality of Life: A Study Protocol

José Pedro Ferreira et al. Front Public Health. .

Abstract

Physical exercise has shown positive effects on symptomatology and on the reduction of comorbidities in population with autism spectrum disorder (ASD). However, there is still no consensus about the most appropriate exercise intervention model for children with ASD. The physical exercise program for children with autism (PEP-Aut) protocol designed allow us to (i) examine the multivariate associations between ASD symptoms, metabolic profile, physical activity level, physical fitness, and health-related quality of life of children with ASD; (ii) assess the effects of a 40-week exercise program on all these aspects of children with ASD. The impact of the exercise program will be assessed based on the sequence of the two phases. Phase 1 is a 12-week cross-sectional study assessing the symptomatology, metabolic profile, physical fitness and physical activity levels, socioeconomic status profile, and health-related quality of life of participants. This phase is the baseline of the following phase. Phase 2 is a 48-week intervention study with a 40-week intervention with exercise that will take place in a specialized center for children with ASD in the city of Maceió-Alagoas, Brazil. The primary outcomes will be change in the symptomatic profile and the level of physical activity of children. Secondary outcomes will be anthropometric and metabolic profiles, aerobic function, grip strength, socioeconomic status, and health-related quality of life. The study will provide critical information on the efficacy of exercise for children with ASD and help guide design and delivery of future programs.

Keywords: autism spectrum disorders; biomarkers; exercise; intervention studies; quality of life; stereotypes.

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Figures

Figure 1
Figure 1
Timeline of the PEP-Aut’s phases (cross-sectional and intervention).
See this image and copyright information in PMC

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