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. 2018 Aug;15(8):737-739.
doi: 10.1038/cmi.2017.159. Epub 2018 Mar 19.

Cellular origin of glioblastoma and its implication in precision therapy

Maojin Yao  1 , Shu Li  2 , Xiaojun Wu  3 , Shuo Diao  1   4 , Guoxin Zhang  5 , Hua He  6   7 , Liuguan Bian  8 , Yicheng Lu  3
Affiliations

Cellular origin of glioblastoma and its implication in precision therapy

Maojin Yao et al. Cell Mol Immunol. 2018 Aug.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic of platform based on cellular origin. Dissociated tumor cells were divided into two populations. One half was injected into immunodeficient mice, and the other was cultured in several conditions. When doing drug screening, the candidate that shows great potential in either condition should be validated in a patient-derived xenografting (PDX) model in vivo. After validation in PDX, the remaining candidates should move to clinical trials in glioma patients.
See this image and copyright information in PMC

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