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. 2018 Apr;24(4):798-800.
doi: 10.3201/eid2404.171319.

Classical Swine Fever Outbreak after Modified Live LOM Strain Vaccination in Naive Pigs, South Korea

Sang H Je, Taeyong Kwon, Sung J Yoo, Dong-Uk Lee, SeungYoon Lee, Juergen A Richt, Young S Lyoo

Classical Swine Fever Outbreak after Modified Live LOM Strain Vaccination in Naive Pigs, South Korea

Sang H Je et al. Emerg Infect Dis. 2018 Apr.

Abstract

We report classical swine fever outbreaks occurring in naive pig herds on Jeju Island, South Korea, after the introduction of the LOM vaccine strain. Two isolates from sick pigs had >99% identity with the vaccine stain. LOM strain does not appear safe; its use in the vaccine should be reconsidered.

Keywords: Jeju Island; LOM strain; South Korea; classical swine fever; classical swine fever virus; livestock; modified live vaccine; outbreak; pigs; residual virulence; vaccination; viruses.

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Figures

Figure
Figure
Clinical signs and pathologic lesions in naive pig infected with classical swine fever virus LOM vaccine strain, Jeju Island, South Korea. A) Cyanosis of ear. B) Hemorrhages in kidney. C) Marginal infarction of spleen. D) Button ulcers in large intestine. E) Hemorrhages in bladder.
See this image and copyright information in PMC

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