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. 2018 Apr;24(4):804-806.
doi: 10.3201/eid2404.171817.

Cephalosporin-Resistant Neisseria gonorrhoeae Clone, China

Shao-Chun Chen, Yue-Ping Yin, Xiang-Sheng Chen

Cephalosporin-Resistant Neisseria gonorrhoeae Clone, China

Shao-Chun Chen et al. Emerg Infect Dis. 2018 Apr.

Abstract

Cephalosporin-resistant Neisseria gonorrhoeae is a major public health concern. N. gonorrhoeae of multiantigen sequence type G1407 and multilocus sequence type 1901 is an internationally spreading cephalosporin-resistant clone. We detected 4 cases of infection with this clone in China and analyzed resistance determinants by using N. gonorrhoeae sequence typing for antimicrobial resistance.

Keywords: China; MLST 1901; N. gonorrhoeae multiantigen sequence type; NG-MAST G1407; Neisseria gonorrhoeae; antimicrobial resistance; bacteria; extended-spectrum cephalosporin; gonorrhea; internationally spread clone; multilocus sequence type; sexual transmitted infections.

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References

    1. Chinese Center for Disease Control and Prevention. Epidemic of infectious diseases in China, 2016. [2018 Jan 12]. http://www.nhfpc.gov.cn/jkj/s3578/201702/38ca5990f8a54ddf9ca6308fec40615...
    1. Wang QQ, Zhang GC. Guidelines for diagnosis and treatment of sexually transmitted diseases [in Chinese]. Shanghai: Shanghai Science and Technology Press; 2007.
    1. Chen SC, Yin YP, Dai XQ, Unemo M, Chen XS. Antimicrobial resistance, genetic resistance determinants for ceftriaxone and molecular epidemiology of Neisseria gonorrhoeae isolates in Nanjing, China. J Antimicrob Chemother. 2014;69:2959–65. 10.1093/jac/dku245 - DOI - PubMed
    1. Chen SC, Yin YP, Dai XQ, Unemo M, Chen XS. First nationwide study regarding ceftriaxone resistance and molecular epidemiology of Neisseria gonorrhoeae in China. J Antimicrob Chemother. 2016;71:92–9. 10.1093/jac/dkv321 - DOI - PubMed
    1. Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother. 2012;56:1273–80. 10.1128/AAC.05760-11 - DOI - PMC - PubMed

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