[An update on myasthenia gravis]

Abstract

Myasthenia gravis is one of the most common disorders that affect neuromuscular transmission. It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue that affects a combination of ocular muscles, bulbar functions, as well as limb and respiratory muscles, which are due to an immune attack against the postsynaptic membrane of the neuromuscular junction. The diagnosis of myasthenia gravis is based on clinical and serological test. It is a disease that can be effectively controlled with the current therapeutic lines, even achieving a complete remission. An update of this interesting disorder is now presented.

Keywords: Acetilcolina; Acetylcholine; Autoantibodies; Autoanticuerpos; Debilidad muscular; Miastenia gravis; Muscle weakness; Myasthenia gravis.