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. 2018 Apr;15(4):3765-3768.
doi: 10.3892/etm.2018.5874. Epub 2018 Feb 15.

A probe into effect of Shoutai pill on endometrial receptivity

Lijun Zhao  1 , Yang Xu  1 , Xiaoling Duo  1 , Xiaoying Tian  2 , Peng Wang  3
Affiliations

A probe into effect of Shoutai pill on endometrial receptivity

Lijun Zhao et al. Exp Ther Med. 2018 Apr.

Abstract

The effect of Shoutai pill on endometrial receptivity was analyzed. A total of 160 patients with spontaneous abortion were enrolled in this study. They were treated in the Fifth People's Hospital of Jinan (Shandong, China) from February 2014 to June 2016. The following treatment regimen was performed for the patients: after menstruation, Shoutai pill was taken as continuous medication for more than 5 menstrual cycles, the pill was taken 20 days per month, medication was stopped during menstruation, and contraceptive measures were taken during this period. Statistics were recorded of endometrial thickness and morphology, hemodynamic parameters of uterine spiral artery, including pulsatility index (PI) and resistance index (RI), endometrial LIF levels before and after treatment, and follicular development and ovulation were strictly monitored, and statistics of pregnancy were recorded. The endometrial thickness, type A endometrium and endometrial spiral arterial PI and RI levels, endometrial LIF levels were significantly improved after treatment (P<0.05); at the same time, pregnancy rate was 85%; during this treatment, patients had no significant side effects. In conclusion, improvement of endometrial acceptability with Shoutai pills can receive good effect, significantly promote embryo implantation and enhance pregnancy rate.

Keywords: Shoutai pill; endometrial receptivity; spontaneous abortion; treatment effect.

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Figures

Figure 1.
Figure 1.
Anti-endometrial antibody.
Figure 2.
Figure 2.
Endometrium.
Figure 3.
Figure 3.
Embryo implantation.
Figure 4.
Figure 4.
Expression of endometrial LIF.
See this image and copyright information in PMC

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