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Review
. 2018 Feb;18(1):1-8.
doi: 10.17245/jdapm.2018.18.1.1. Epub 2018 Feb 27.

The effect of pre- and after-treatment of sevoflurane on central ischemia tolerance and the underlying mechanisms

Hao Xu  1 , Xiao-Peng Mei  2 , Li-Xian Xu  3
Affiliations
Review

The effect of pre- and after-treatment of sevoflurane on central ischemia tolerance and the underlying mechanisms

Hao Xu et al. J Dent Anesth Pain Med. 2018 Feb.

Abstract

In recent years, with continuous research efforts targeted at studying the effects of pre- and after-treatment of inhaled anesthetics, significant progress has been made regarding the common clinical use of low concentrations of inhaled sevoflurane and its effect on induced central ischemia tolerance by pre- and post-treatment. In this study, we collected, analyzed, classified, and summarized recent literature regarding the effect of sevoflurane on central ischemia tolerance and its related mechanisms. In addition, we provide a theoretical basis for the clinical application of sevoflurane to protect the central nervous system and other important organs against ischemic injury.

Keywords: Central Nervous System; Ischemia; Sevoflurane; Tolerance.

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Conflict of interest statement

NOTES: There are no financial or other issues that might lead to conflict of interest.

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