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Comparative Study
. 1987 Apr;31(4):640-2.
doi: 10.1128/AAC.31.4.640.

In vitro activity of A-56268 (TE-031), a new macrolide antibiotic, compared with that of erythromycin and other antimicrobial agents

S Floyd-Reising, J A Hindler, L S Young
Comparative Study

In vitro activity of A-56268 (TE-031), a new macrolide antibiotic, compared with that of erythromycin and other antimicrobial agents

S Floyd-Reising et al. Antimicrob Agents Chemother. 1987 Apr.

Abstract

A-56268 is a new macrolide antibiotic that resembles erythromycin in its spectrum of activity. A-56268 and erythromycin had identical activities against Streptococcus pyogenes, group B, C, and G streptococci, and viridans group streptococci. Erythromycin and A-56268 had similar activities against Staphylococcus aureus, coagulase-negative staphylococci, and group D enterococci. Like erythromycin, A-56268 was ineffective in inhibiting oxacillin-resistant S. aureus, oxacillin-resistant, coagulase-negative staphylococci, and penicillin-resistant viridans group streptococci. Haemophilus influenzae, Neisseria gonorrhoeae, and Legionella spp. were inhibited by A-56268 at concentrations similar to those of erythromycin.

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References

    1. Antimicrob Agents Chemother. 1982 Jul;22(1):90-3 - PubMed
    1. Antimicrob Agents Chemother. 1984 Apr;25(4):529-31 - PubMed
    1. Antimicrob Agents Chemother. 1983 Aug;24(2):209-15 - PubMed

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