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. 2018 Dec;183(6):961-965.
doi: 10.1007/s11046-018-0260-y. Epub 2018 Mar 20.

Mycetoma in the Togolese: An Update from a Single-Center Experience

Tchin Darré  1   2 , Bayaki Saka  3 , Abas Mouhari-Toure  3 , Mazamaesso Tchaou  4 , Améyo Monique Dorkenoo  5 , Kwamé Doh  6 , Atchi Walla  7 , Koffi Amégbor  6 , Vincent Palokinam Pitché  3 , Gado Napo-Koura  6
Affiliations

Mycetoma in the Togolese: An Update from a Single-Center Experience

Tchin Darré et al. Mycopathologia. 2018 Dec.

Abstract

Background: Mycetoma is a chronic inflammatory process caused either by fungi (eumycetoma) or bacteria (actinomycetoma). In this retrospective study, we report epidemiologic and histopathological data of mycetoma observed in the Lome Hospital, Togo in a 25-year period (1992-2016).

Methodology: This is a retrospective study, over a period of 25 years, to analyze epidemiological and etiological findings of mycetomas seen in the single laboratory of pathological anatomy of the Lomé, Togo.

Results: A total of 61 cases were retrieved from which only 33 cases were included which where clinically and microbiologically confirmed. The mean age of the patients was 29.7 ± 1.34 and a sex ratio (M/F) of 1.5. The majority of patients were farmers (n = 23 cases; 69.7%). Diagnosed etiologic agents were fungal in 24 cases (72.7%) and actinomycotic cases in 9 cases (27.3%). The fungal mycetomas consisted of Madurella mycetomatis (black grains) and Falcifomispora senegaliensis (black grains). The actinomycotic agents were represented by Actinomadura madurae (white grains), Actinomadurae pelletieri (red grains) and Nocardia sp. (yellow grains).

Conclusion: This report represents a single-center study which provides epidemiologic and histopathological data of mycetoma cases in Togo.

Keywords: Epidemiology; Etiological agents; Mycetomas; Togo.

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Conflict of interest statement

Conflict of interest

The authors declare that they have no competing interests.

Availability of Data and Materials

The datasets supporting the conclusions of this article are included within the manuscript and its supporting material.

Consent for Publication

The Department of Pathology of Teaching Hospital of Lomé authorized the publication of this manuscript.

Ethical Consideration

This study received approval from the head of the laboratory department to be conducted (Ref No. 08/2017/LAP/CHUSO). Since it was counting records, patient consent was not required. However, during the counting and data collection patient names were not collected in order to preserve confidentiality. The manuscript has not been submitted to more than one review for simultaneous review and has not been published before. Only one study is not divided into several parts, and no data have been produced.

Figures

Fig. 1
Fig. 1
Photography showing the mycetoma triad of mass, multiple discharging sinuses and black grains due to M. mycetomatis
Fig. 2
Fig. 2
Photography showing the mycetoma of the foot in A. pelletieri
Fig. 3
Fig. 3
Photomicrograph showing M. mycetomatis in tissue section (H and E, × 100)
Fig. 4
Fig. 4
Photomicrograph showing A. madurae in tissue section (H and E, × 100)
Fig. 5
Fig. 5
Radiography of feet showing bone destruction
See this image and copyright information in PMC

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References

    1. Lichon V, Khachemoune A. Mycetoma: a review. Am J Clin Dermatol. 2006;7(5):315–321. doi: 10.2165/00128071-200607050-00005. - DOI - PubMed
    1. van de Sande WW, el Maghoub S, Fahal AH, Goodfellow M, Welsh O, Zijlstra E. The mycetoma knowledge gap: identification of research priorities. PLoS Negl Trop Dis. 2014;8(3):e2667. doi: 10.1371/journal.pntd.0002667. - DOI - PMC - PubMed
    1. Fahal A, el Mahgoub S, El Hassan AM, Abdel-Rahman ME, Alshambaty Y, Hashim A, et al. New model for management of mycetoma in the Sudan. PLoS Negl Trop Dis. 2014;8(10):e3271. doi: 10.1371/journal.pntd.0003271. - DOI - PMC - PubMed
    1. Mahe A, Develoux M, Lienhardt C, Keita S, Bobin P. Mycetomas in Mali: causative agents and geographic distribution. Am J Trop Med Hyg. 1996;54(1):77–79. doi: 10.4269/ajtmh.1996.54.77. - DOI - PubMed
    1. Zarei Mahmoudabadi A, Zarrin M. Mycetomas in Iran: a review article. Mycopathologia. 2008;165(3):135–141. doi: 10.1007/s11046-007-9066-z. - DOI - PubMed

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