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. 2018 Jan-Apr;11(1):38-41.
doi: 10.4103/ojo.OJO_27_2017.

Comparison of choroidal thickness using swept-source and spectral-domain optical coherence tomography in normal Indian eyes

Siddharth Narendran  1 , George Manayath  1 , Narendran Venkatapathy  1
Affiliations

Comparison of choroidal thickness using swept-source and spectral-domain optical coherence tomography in normal Indian eyes

Siddharth Narendran et al. Oman J Ophthalmol. 2018 Jan-Apr.

Abstract

Background/aims: Choroidal thickness measurements are reported to differ between spectral-domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT). The aim of this study was to assess the comparability of choroidal thickness measurements using SS-OCT and SD-OCT devices among normal participants.

Materials and methods: This was a prospective study of 31 (62 eyes) normal participants. Choroidal imaging was performed sequentially with the Spectralis OCT (SD-OCT) and the deep range imaging OCT (DRI OCT-1) (SS-OCT) using standardized imaging protocols. The subfoveal choroidal thickness (SFChT) was measured manually by two masked retinal specialists. Paired t-tests and intraclass correlation coefficients (ICCs) were used to compare the measurements.

Results: The mean SFChT was 319.5 μm and 325.3 μm for DRI OCT-1 and Spectralis OCT, respectively (P = 0.001), with a mean difference of 5.9 with ICC of 0.97. The mean difference in choroidal thickness between the OCT devices was larger among eyes with choroidal thickness > 350 μm compared with eyes with thinner choroids (8.0 μm vs. 4.7 μm).

Conclusions: SFChT measurements are comparable between DRI OCT-1 and Spectralis OCT. The variability between the devices increases in thicker choroids.

Keywords: Choroidal thickness; spectral-domain optical coherence tomography; swept-source optical coherence tomography.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Optical coherence tomography image showing the measurement of the subfoveal choroidal thickness
Figure 2
Figure 2
Grading of the optical coherence tomography images was done based on the visibility of the chorioscleral interface Grade 1: <25% chorioscleral interface visible, Grade 2: 25%–50% chorioscleral interface visible, Grade 3: 50%–75% chorioscleral interface visible, Grade 4: >75% visible
Figure 3
Figure 3
Scatter plot with subfoveal choroidal thickness sorted by spectralis optical coherence tomography and plotted against deep range imaging-1 optical coherence tomography
See this image and copyright information in PMC

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