A Novel Scoring System Approach to Assess Patients with Lyme Disease (Nutech Functional Score)
- PMID: 29563715
- PMCID: PMC5850763
- DOI: 10.4103/jgid.jgid_11_17
A Novel Scoring System Approach to Assess Patients with Lyme Disease (Nutech Functional Score)
Abstract
Introduction: A bacterial infection by Borrelia burgdorferi referred to as Lyme disease (LD) or borreliosis is transmitted mostly by a bite of the tick Ixodes scapularis in the USA and Ixodes ricinus in Europe. Various tests are used for the diagnosis of LD, but their results are often unreliable. We compiled a list of clinically visible and patient-reported symptoms that are associated with LD. Based on this list, we developed a novel scoring system.
Methodology: Nutech functional Score (NFS), which is a 43 point positional (every symptom is subgraded and each alternative gets some points according to its position) and directional (moves in direction bad to good) scoring system that assesses the patient's condition.
Results: The grades of the scoring system have been converted into numeric values for conducting probability based studies. Each symptom is graded from 1 to 5 that runs in direction BAD → GOOD.
Conclusion: NFS is a unique tool that can be used universally to assess the condition of patients with LD.
Keywords: Borrelia burgdorferi-antibodies; Lyme disease; Nutech functional score; human embryonic stem cells.
Conflict of interest statement
There are no conflicts of interest.
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References
-
- Derdáková M, Lencáková D. Association of genetic variability within the Borrelia burgdorferi sensu lato with the ecology, epidemiology of Lyme borreliosis in Europe. Ann Agric Environ Med. 2005;12:165–72. - PubMed
-
- Seibel MM, Smith DM, Levesque L, Borten M, Taymor ML. The temporal relationship between the luteinizing hormone surge and human oocyte maturation. Am J Obstet Gynecol. 1982;142:568–72. - PubMed
-
- Steere AC. Lyme disease. N Engl J Med. 2001;345:115–25. - PubMed
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