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Review
. 2017 Oct 31;2017(3):e201720.
doi: 10.21542/gcsp.2017.20.

The global epidemiology of Kawasaki disease: Review and future perspectives

Affiliations
Review

The global epidemiology of Kawasaki disease: Review and future perspectives

Ming-Tai Lin et al. Glob Cardiol Sci Pract. .

Abstract

Kawasaki disease (KD) is one of the most common childhood vasculitides and may lead to coronary arterial complications. KD has been reported in more than 60 countries over five continents. Previous publications have provided a comprehensive description of the epidemiologic features of KD including incidence, age of onset, seasonal trends, and rates of cardiac lesions. However, the interactions among the KD patients, time (seasons) and place have been less well studied. We review the current global epidemiology of KD and focus on the longitudinal changes in incidence, seasonality and response to intravenous immunoglobulin (IVIG) therapy.

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Figures

Figure 1.
Figure 1.. (A) Worldwide incidence of Kawasaki disease per 100,000 children younger than 5 years old; (B) Worldwide percentage of IVIG resistance in the children with Kawasaki disease.

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