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. 2018 Apr;20(4):314-316.
doi: 10.1089/dia.2017.0455. Epub 2018 Mar 22.

Optimal Sampling Duration for Continuous Glucose Monitoring to Determine Long-Term Glycemic Control

Tonya D Riddlesworth  1 , Roy W Beck  1 , Robin L Gal  1 , Crystal G Connor  1 , Richard M Bergenstal  2 , Sooji Lee  3 , Steven M Willi  3
Affiliations

Optimal Sampling Duration for Continuous Glucose Monitoring to Determine Long-Term Glycemic Control

Tonya D Riddlesworth et al. Diabetes Technol Ther. 2018 Apr.

Abstract

Objective: To determine the minimum sample of continuous glucose monitoring (CGM) data needed to accurately reflect 3 months of glycemic control.

Research design and methods: Three months of CGM data were collected on 257 individuals (age 10-78 years) with type 1 diabetes in two studies (one using the Abbott FreeStyle Libre Pro™ and the other using the Dexcom™ G4). Correlations were calculated between the full 3 months and incremental sampling periods of CGM data.

Results: Correlation to the full 3 months of data improved with an increasing number of days of data collection, plateauing by about 14 days, with an R2 value of 0.84-0.86 for mean glucose, time at 70-180 mg/dL, and time >180 mg/dL, with lower values for time <70 mg/dL (0.76) and coefficient of variation (0.70).

Conclusions: Fourteen days of CGM data provide a good estimation of glucose metrics for a 3-month period.

Keywords: Continuous glucose monitoring; Data sampling; Type 1 diabetes.

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