Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2018 Mar 23;19(4):959.
doi: 10.3390/ijms19040959.

Oxidative Stress and Space Biology: An Organ-Based Approach

Thomas J Goodwin  1 , Melpo Christofidou-Solomidou  2
Affiliations
Editorial

Oxidative Stress and Space Biology: An Organ-Based Approach

Thomas J Goodwin et al. Int J Mol Sci. .

Abstract

The environment of space provides many challenges to the human physiology and therefore to extended habitation and exploration[...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
This graphic depiction of human disease states linked to Oxidative Stress and Damage (OSaD) reflects the categories and similarities, although to a lesser degree, experienced by astronauts. Adapted from National Institute of Standards and Technology (NIST)6.
Figure 2
Figure 2
This illustration demonstrates the general construct of the space suit and the lack of substantive shielding leading to increased radiation exposure and generation of OSaD. Courtesy of NASA Johnson Space Center.
See this image and copyright information in PMC

References

    1. Hawkins W., Zieglschmid J. Clinical aspects of crew health. In: Johnston R., Dietlein L., Berry C., editors. Biomedical Results of Apollo. National Aeronautics and Space Administration; Washington, DC, USA: 1975. pp. 43–81.
    1. Kimzey S.L. Hematology and immunology studies. In: Johnson R.S., Dietlein L.F., editors. Biomedical Results from Skylab. National Aeronautics and Space Administration; Washington, DC, USA: 1977. pp. 248–282.
    1. Thirsk R., Kuipers A., Mukai C., Williams D. The space-flight environment: The International Space Station and beyond. CMAJ Can. Med. Assoc. J. 2009;180:1216–1220. doi: 10.1503/cmaj.081125. - DOI - PMC - PubMed
    1. Williams D., Kuipers A., Mukai C., Thirsk R. Acclimation during space flight: Effects on human physiology. CMAJ Can. Med. Assoc. J. 2009;180:1317–1323. doi: 10.1503/cmaj.090628. - DOI - PMC - PubMed
    1. Demontis G.C., Germani M.M., Caiani E.G., Barravecchia I., Passino C., Angeloni D. Human Pathophysiological Adaptations to the Space Environment. Front. Physiol. 2017;8:547. doi: 10.3389/fphys.2017.00547. - DOI - PMC - PubMed

Publication types

LinkOut - more resources