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. 2018 Sep:199:341-345.
doi: 10.1016/j.schres.2018.03.014. Epub 2018 Mar 20.

Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study

J M Lappin  1 , M Heslin  2 , B Lomas  3 , P B Jones  4 , G A Doody  5 , U A Reininghaus  6 , T Croudace  7 , T Craig  2 , P Fearon  8 , R M Murray  9 , P Dazzan  2 , C Morgan  2
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Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study

J M Lappin et al. Schizophr Res. 2018 Sep.

Abstract

Objective: To describe the characteristics of individuals with early sustained recovery following first episode psychosis.

Methods: Individuals with a first episode psychosis were followed-up for ten years. Comparisons were made between those with Early Sustained Recovery and those with Other Course types.

Results: Of 345 individuals, n=43 (12.5%) had Early Sustained Recovery. They were more likely than those with Other Course types to be female (OR=2.45; 95% CI: 1.25-4.81); employed (OR=2.39; 95% CI: 1.22-4.69); in a relationship (OR=2.68; 95% CI: 1.35-5.32); have a short DUP (OR=2.86; 95% CI: 1.37-5.88); and have a diagnosis other than schizophrenia, particularly mania (OR=6.39; 95% CI: 2.52-16.18) or brief psychosis (OR=3.64; 95% CI: 1.10-12.10).

Conclusions: Sustained recovery from first episode psychosis occurs in a minority.

Keywords: Longitudinal follow-up; Medication; Outcomes; Psychosis; Recovery; Schizophrenia.

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