Comparative Study
doi: 10.1038/329301a0.
Insulin-like growth factor II receptor as a multifunctional binding protein
- PMID: 2957598
- DOI: 10.1038/329301a0
Item in Clipboard
Comparative Study
Insulin-like growth factor II receptor as a multifunctional binding protein
Nature.
1987 Sep.
Abstract
The primary structure of human insulin-like growth factor II receptor, predicted from the complementary DNA sequence, reveals a transmembrane receptor molecule with a large extracellular domain made up of fifteen repeat sequences and a small region homologous to the collagen-binding domain of fibronectin. The structural and biochemical features of the IGF-II receptor appear identical to those of the cation-independent mannose-6-phosphate receptor.
Similar articles
-
A single receptor binds both insulin-like growth factor II and mannose-6-phosphate.Science. 1988 Mar 4;239(4844):1134-7. doi: 10.1126/science.2964083. Science. 1988. PMID: 2964083
-
The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.J Biol Chem. 1988 Feb 15;263(5):2553-62. J Biol Chem. 1988. PMID: 2963003
-
The mouse insulin-like growth factor II/cation-independent mannose 6-phosphate (IGF-II/MPR) receptor gene: molecular cloning and genomic organization.Genomics. 1994 Jan 1;19(1):120-9. doi: 10.1006/geno.1994.1021. Genomics. 1994. PMID: 8188212
-
Mannose 6-phosphate receptors and their role in targeting proteins to lysosomes.J Membr Biol. 1988 Jul;103(1):7-16. doi: 10.1007/BF01871928. J Membr Biol. 1988. PMID: 2972840 Review. No abstract available.
-
The insulin receptor: from protein sequence to structure.Biochem Soc Trans. 1999 Aug;27(4):715-26. doi: 10.1042/bst0270715. Biochem Soc Trans. 1999. PMID: 10917671 Review.
Cited by
-
Insulin-like growth factor binding to the atypical insulin receptors of a human lymphoid-derived cell line (IM-9).Biochem J. 1990 Mar 15;266(3):737-42. doi: 10.1042/bj2660737. Biochem J. 1990. PMID: 2327961 Free PMC article.
-
Cathepsin D: a protease involved in breast cancer metastasis.Cancer Metastasis Rev. 1990 Dec;9(4):321-31. doi: 10.1007/BF00049522. Cancer Metastasis Rev. 1990. PMID: 1965795 Review.
-
Mutations in the IGF-II pathway that confer resistance to lytic reovirus infection.BMC Cell Biol. 2004 Aug 27;5:32. doi: 10.1186/1471-2121-5-32. BMC Cell Biol. 2004. PMID: 15333144 Free PMC article.
-
Origin of fibronectin type II (FN2) modules: structural analyses of distantly-related members of the kringle family idey the kringle domain of neurotrypsin as a potential link between FN2 domains and kringles.Protein Sci. 2001 Oct;10(10):2114-22. doi: 10.1110/ps.15801. Protein Sci. 2001. PMID: 11567102 Free PMC article.
-
Keys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.Am J Pathol. 2003 Jan;162(1):3-6. doi: 10.1016/S0002-9440(10)63791-1. Am J Pathol. 2003. PMID: 12507883 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
