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. 2018 Jul;12(4):497-500.
doi: 10.1016/j.dsx.2018.03.015. Epub 2018 Mar 16.

Relationship between serum levels of oxidative stress and metabolic syndrome components

Maryam Abbasian  1 , Mehri Delvarianzadeh  2 , Hossein Ebrahimi  3 , Farideh Khosravi  4 , Pirasteh Nourozi  5
Affiliations

Relationship between serum levels of oxidative stress and metabolic syndrome components

Maryam Abbasian et al. Diabetes Metab Syndr. 2018 Jul.

Abstract

Aims: This study aimed to investigate the relationship between the total antioxidant capacity (TAC) and Malondialdehyde (MDA) with number of metabolic syndrome (Mets) components on the personnel working in Shahroud University of Medical Sciences.

Methods: This cross-sectional study was conducted on 167 personnel aged 30-60 years old. ATP III criteria were used to diagnose patients with MetS. Oxidative stress indicators were measured. The data was analyzed via one-way ANOVA, and Pearson and Spearman correlation coefficients.

Results: The result showed that TAC had a significant positive correlation with HDL and a significant negative correlation with abdominal obesity. In addition, there was a significant positive association between the level of MDA and age, BMI, abdominal obesity, diastolic blood pressure, triglycerides, and LDL; however, it had a negative significant correlation with HDL.

Conclusions: The measurement of TAC and MDA biomarkers can increase the early diagnosis of patients at risk of developing Mets.

Keywords: Metabolic syndrome; Metabolic syndrome components; Oxidative stress.

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