Circulating microbiome in blood of different circulatory compartments

Robert Schierwagen¹, Camila Alvarez-Silva², Mette Simone Aae Madsen², Carl Christian Kolbe³, Carsten Meyer⁴, Daniel Thomas⁴, Frank Erhard Uschner¹, Fernando Magdaleno¹, Christian Jansen¹, Alessandra Pohlmann¹, Michael Praktiknjo¹, Gunnar T Hischebeth^{5

6}, Ernst Molitor^{5

6}, Eicke Latz^{3

7

8}, Benjamin Lelouvier⁹, Jonel Trebicka^{1

10

11

12}, Manimozhiyan Arumugam²

Affiliations

¹ Department of Internal Medicine I, University of Bonn, Bonn, Germany.
² The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
³ Institute of Innate Immunity, University of Bonn, Bonn, Germany.
⁴ Department of Radiology, University of Bonn, Bonn, Germany.
⁵ Institute of Medical Microbiology, Immunology and Parasitology, University of Bonn, Bonn, Germany.
⁶ Partner site Cologne-Bonn, German Center of Infection Research (DZIF), Bonn, Germany.
⁷ Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
⁸ Centre for Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
⁹ Vaiomer, Labège, France.
¹⁰ European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.
¹¹ Institute for Bioengineering of Catalonia, Barcelona, Spain.
¹² Department of Medical Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.

Comment

Robert Schierwagen et al. Gut. 2019 Mar.

. 2019 Mar;68(3):578-580.

doi: 10.1136/gutjnl-2018-316227. Epub 2018 Mar 26.

¹ Department of Internal Medicine I, University of Bonn, Bonn, Germany.
² The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
³ Institute of Innate Immunity, University of Bonn, Bonn, Germany.
⁴ Department of Radiology, University of Bonn, Bonn, Germany.
⁵ Institute of Medical Microbiology, Immunology and Parasitology, University of Bonn, Bonn, Germany.
⁶ Partner site Cologne-Bonn, German Center of Infection Research (DZIF), Bonn, Germany.
⁷ Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
⁸ Centre for Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
⁹ Vaiomer, Labège, France.
¹⁰ European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.
¹¹ Institute for Bioengineering of Catalonia, Barcelona, Spain.
¹² Department of Medical Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.

No abstract available

Keywords: bacterial translocation; chronic liver disease; inflammation; intestinal microbiology; portal hypertension.

Comment in

Response to: 'Circulating microbiome in blood of different circulatory compartments' by Schierwagen et al.
Hornung BVH, Zwittink RD, Ducarmon QR, Kuijper EJ. Hornung BVH, et al. Gut. 2020 Apr;69(4):789-790. doi: 10.1136/gutjnl-2019-318601. Epub 2019 Apr 6. Gut. 2020. PMID: 30954950 No abstract available.
Trust is good, control is better: technical considerations in blood microbiome analysis.
Schierwagen R, Alvarez-Silva C, Servant F, Trebicka J, Lelouvier B, Arumugam M. Schierwagen R, et al. Gut. 2020 Jul;69(7):1362-1363. doi: 10.1136/gutjnl-2019-319123. Epub 2019 Jun 15. Gut. 2020. PMID: 31203205 Free PMC article. No abstract available.

Gut microbiome and liver diseases.
Tilg H, Cani PD, Mayer EA. Tilg H, et al. Gut. 2016 Dec;65(12):2035-2044. doi: 10.1136/gutjnl-2016-312729. Epub 2016 Oct 8. Gut. 2016. PMID: 27802157 Review.