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Case Reports
. 2018 Mar 22;2018(3):omx108.
doi: 10.1093/omcr/omx108. eCollection 2018 Mar.

Life-threatening hemoptysis: case of Osler-Weber-Rendu Syndrome

Ricardo Alicea-Guevara  1 , Michael Cruz Caliz  2 , Jose Adorno  2 , Ricardo Fernandez  2 , Kelvin Rivera  2 , Gustavo Gonzalez  2 , Ricardo Alan Hernandez-Castillo  2 , Rosangela Fernandez  2 , Christian Castillo Latorre  2
Affiliations
Case Reports

Life-threatening hemoptysis: case of Osler-Weber-Rendu Syndrome

Ricardo Alicea-Guevara et al. Oxf Med Case Reports. .

Abstract

Hereditary haemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is a rare autosomal dominant vascular disorder. Patients with HHT may present with a wide spectrum of clinical manifestations, some considered to be life-threatening. We present the case of a 53-year-old male who presented with massive haemoptysis. Chest computed tomography scan was remarkable for a large anterior, left lower lobe arteriovenous malformation. The patient underwent a pulmonary angiogram with embolization of a large left lung arteriovenous malformation, which proved to be successful in controlling the bleeding.

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Figures

Figure 1:
Figure 1:
Multiple mucosal hemorrhagic telangiectasias, more prominent on the right lateral aspect of the tongue
Figure 2:
Figure 2:
Chest computer tomography shows left lower lung pulmonary AVM (black circle)
Figure 3:
Figure 3:
Pre-embolectomy fluoroscopy image showing afferent artery with the presence of aneurysm with feeding effect
Figure 4:
Figure 4:
Post-embolectomy fluoroscopy image showing afferent artery without signs of perfusion or feeding
Figure 5:
Figure 5:
Chest computer tomography showing status post-embolectomy of pulmonary AVM (black circle)
See this image and copyright information in PMC

References

    1. Shovlin CL. Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment. Blood Rev 2010;24:203 DOI:10.1016/j.blre.2010.07.001. - DOI - PubMed
    1. Faughnan ME, Palda VA, Garcia-Tsao G, Geisthoff UW, McDonald J, Proctor DD, et al. International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia. J Med Genet 2011;48:73–87. DOI:10.1136/jmg.2009.069013. - DOI - PubMed
    1. Lacombe P, Lacout A, Marcy PY, Binsse S, Sellier J, Bensalah M, et al. Diagnosis and treatment of pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: an overview. Diagn Interv Imaging 2013;94:835 DOI:10.1016/j.diii.2013.03.014. - DOI - PubMed
    1. Trembath RC, Thomson JR, Machado RD, Morgan NV, Atkinson C, Winship I, et al. Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia. N Engl J Med 2001;345:325–34. DOI:10.1056/NEJM200108023450503. - DOI - PubMed
    1. Cottin V, Chinet T, Lavolé A, Corre R, Marchand E, Reynaud-Gaubert M, et al. Pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: a series of 126 patients. Medicine (Baltimore) 2007;86:1–17. DOI:10.1097/MD.0b013e31802f8da1. - DOI - PubMed

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