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. 2018 Mar;97(13):e0224.
doi: 10.1097/MD.0000000000010224.

Integrative medicine for managing the symptoms of lupus nephritis: A protocol for systematic review and meta-analysis

Tae-Young Choi  1 , Ji Hee Jun, Myeong Soo Lee
Affiliations

Integrative medicine for managing the symptoms of lupus nephritis: A protocol for systematic review and meta-analysis

Tae-Young Choi et al. Medicine (Baltimore). 2018 Mar.

Abstract

Background: Integrative medicine is claimed to improve symptoms of lupus nephritis. No systematic reviews have been performed for the application of integrative medicine for lupus nephritis on patients with systemic lupus erythematosus (SLE). Thus, this review will aim to evaluate the current evidence on the efficacy of integrative medicine for the management of lupus nephritis in patients with SLE.

Methods and analyses: The following electronic databases will be searched for studies published from their dates of inception February 2018: Medline, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL), as well as 6 Korean medical databases (Korea Med, the Oriental Medicine Advanced Search Integrated System [OASIS], DBpia, the Korean Medical Database [KM base], the Research Information Service System [RISS], and the Korean Studies Information Services System [KISS]), and 1 Chinese medical database (the China National Knowledge Infrastructure [CNKI]). Study selection, data extraction, and assessment will be performed independently by 2 researchers. The risk of bias (ROB) will be assessed using the Cochrane ROB tool.

Dissemination: This systematic review will be published in a peer-reviewed journal and disseminated both electronically and in print. The review will be updated to inform and guide healthcare practice and policy.

Trial registration number: PROSPERO 2018 CRD42018085205.

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Conflict of interest statement

Competing interests: The authors have no conflicts of interest to disclose.

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