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. 2018 Jun;39(6):500-504.
doi: 10.1097/MNM.0000000000000833.

An update on 'dose calibrator' settings for nuclides used in nuclear medicine

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An update on 'dose calibrator' settings for nuclides used in nuclear medicine

Denis E Bergeron et al. Nucl Med Commun. 2018 Jun.

Abstract

Background: Most clinical measurements of radioactivity, whether for therapeutic or imaging nuclides, rely on commercial re-entrant ionization chambers ('dose calibrators'). The National Institute of Standards and Technology (NIST) maintains a battery of representative calibrators and works to link calibration settings ('dial settings') to primary radioactivity standards. Here, we provide a summary of NIST-determined dial settings for 22 radionuclides.

Methods: We collected previously published dial settings and determined some new ones using either the calibration curve method or the dialing-in approach.

Results: The dial settings with their uncertainties are collected in a comprehensive table.

Conclusion: In general, current manufacturer-provided calibration settings give activities that agree with National Institute of Standards and Technology standards to within a few percent.

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