The end for individualized dosing in IVF ovarian stimulation? Reply to letters-to-the-editor regarding the OPTIMIST papers

Affiliations

¹ Department of Reproductive Medicine and Gynecology, University Medical Centre Utrecht, Utrecht University, PO Box 85500, 3508 GA Utrecht, The Netherlands.
² Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, PO Box 85500, 3508 GA Utrecht, The Netherlands.
³ The Robinson Research Institute, School of Pediatrics and Reproductive Health, University of Adelaide, SA 5006 Adelaide, Australia.
⁴ The South Australian Health and Medical Research Unit, PO Box 11060, SA 5001 Adelaide, Australia.

Comment

T C van Tilborg et al. Hum Reprod. 2018.

. 2018 May 1;33(5):984-988.

doi: 10.1093/humrep/dey064.

¹ Department of Reproductive Medicine and Gynecology, University Medical Centre Utrecht, Utrecht University, PO Box 85500, 3508 GA Utrecht, The Netherlands.
² Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, PO Box 85500, 3508 GA Utrecht, The Netherlands.
³ The Robinson Research Institute, School of Pediatrics and Reproductive Health, University of Adelaide, SA 5006 Adelaide, Australia.
⁴ The South Australian Health and Medical Research Unit, PO Box 11060, SA 5001 Adelaide, Australia.

No abstract available

Comment on

OPTIMIST trial: optimistic evidence?
Sunkara SK, Polyzos NP. Sunkara SK, et al. Hum Reprod. 2018 May 1;33(5):983-984. doi: 10.1093/humrep/dey062. Hum Reprod. 2018. PMID: 29596578 No abstract available.
Derailing individualized ovarian stimulation.
Nelson SM, Anderson RA. Nelson SM, et al. Hum Reprod. 2018 May 1;33(5):980-981. doi: 10.1093/humrep/dey060. Hum Reprod. 2018. PMID: 29596619 Free PMC article. No abstract available.
Individualized FSH dosing improves safety and reduces iatrogenic poor response while maintaining live-birth rates.
La Marca A, Blockeel C, Bosch E, Fanchin R, Fatemi HM, Fauser BC, García-Velasco JA, Humaidan P, Tarlatzis BC, Nelson SM. La Marca A, et al. Hum Reprod. 2018 May 1;33(5):982-983. doi: 10.1093/humrep/dey061. Hum Reprod. 2018. PMID: 29596626 No abstract available.
Usefulness of individualized FSH, LH and GH dosing in ovarian stimulation of women with low ovarian reserve.
Mendoza-Tesarik R, Tesarik J. Mendoza-Tesarik R, et al. Hum Reprod. 2018 May 1;33(5):981-982. doi: 10.1093/humrep/dey063. Hum Reprod. 2018. PMID: 29596632 No abstract available.