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Case Reports
. 2018 Mar 27;10(3):388-395.
doi: 10.4254/wjh.v10.i3.388.

Clostridium paraputrificum septicemia and liver abscess

Yong K Kwon  1 , Faiqa A Cheema  2 , Bejon T Maneckshana  2 , Caroline Rochon  2 , Patricia A Sheiner  2
Affiliations
Case Reports

Clostridium paraputrificum septicemia and liver abscess

Yong K Kwon et al. World J Hepatol. .

Abstract

We report the first case of a healthy 23-year-old female who underwent an interventional radiology-guided embolization of a hepatic adenoma, which resulted in a gas forming hepatic liver abscess and septicemia by Clostridium paraputrificum. A retrospective review of Clostridial liver abscesses was performed using a PubMed literature search, and we found 57 clostridial hepatic abscess cases. The two most commonly reported clostridial species are C. perfringens and C. septicum (64.9% and 17.5% respectively). C. perfringens cases carried a mortality of 67.6% with median survival of 11 h, and 70.2% of the C. perfringens cases experienced hemolysis. All C. septicum cases were found to have underlying liver malignancy at the time of the presentation with a mortality of only 30%. The remaining cases were caused by various Clostridium species, and this cohort's clinical course was significantly milder when compared to the above C. perfringens and C. septicum cohorts.

Keywords: Clostridium; Hemolysis; Liver cell adenoma; Morbidity; Mortality; Pyogenic liver abscess.

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Conflict of interest statement

Conflict-of-interest statement: The authors certify that we have no conflict of interest to disclose and did not receive any financial support for this study.

Figures

Figure 1
Figure 1
Magnetic resonance imaging of the segment 7 hepatic adenoma measuring 5.2 cm × 3.3 cm × 6.6 cm.
Figure 2
Figure 2
Computed tomography after stopping oral contraceptive pills for 3 mo. No change in size.
Figure 3
Figure 3
Interventional radiology angiogram of the hepatic adenoma.
Figure 4
Figure 4
The tumor completely replaced by gas pockets.
Figure 5
Figure 5
Follow-up computed tomography. The gas pocket reduced.
See this image and copyright information in PMC

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