Breaking the dose ceiling: proton therapy for locally advanced non-small cell lung cancer

Affiliations

¹ California Protons Cancer Therapy Center, San Diego, CA, USA.
² Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, MD, USA.

Editorial

J Isabelle Choi et al. J Thorac Dis. 2018 Jan.

. 2018 Jan;10(1):130-134.

doi: 10.21037/jtd.2017.12.79.

¹ California Protons Cancer Therapy Center, San Diego, CA, USA.
² Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, MD, USA.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Controversies in dose-escalation for locally advanced non-small cell lung cancer and the role of proton beam therapy.
Verma V, Chang JY. Verma V, et al. J Thorac Dis. 2018 Apr;10(Suppl 9):S1124-S1126. doi: 10.21037/jtd.2018.03.155. J Thorac Dis. 2018. PMID: 29849206 Free PMC article. No abstract available.

Proton Beam Radiotherapy and Concurrent Chemotherapy for Unresectable Stage III Non-Small Cell Lung Cancer: Final Results of a Phase 2 Study.
Chang JY, Verma V, Li M, Zhang W, Komaki R, Lu C, Allen PK, Liao Z, Welsh J, Lin SH, Gomez D, Jeter M, O'Reilly M, Zhu RX, Zhang X, Li H, Mohan R, Heymach JV, Vaporciyan AA, Hahn S, Cox JD. Chang JY, et al. JAMA Oncol. 2017 Aug 10;3(8):e172032. doi: 10.1001/jamaoncol.2017.2032. Epub 2017 Aug 10. JAMA Oncol. 2017. PMID: 28727865 Free PMC article. Clinical Trial.

1. Chang JY, Verma V, Li M, et al. Proton Beam Radiotherapy and Concurrent Chemotherapy for Unresectable Stage III Non-Small Cell Lung Cancer: Final Results of a Phase 2 Study. JAMA Oncol 2017;3:e172032. 10.1001/jamaoncol.2017.2032 - DOI - PMC - PubMed
1. Curran WJ, Jr, Paulus R, Langer CJ, et al. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410. J Natl Cancer Inst 2011;103:1452-60. 10.1093/jnci/djr325 - DOI - PMC - PubMed
1. Furuse K, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 1999;17:2692-9. 10.1200/JCO.1999.17.9.2692 - DOI - PubMed
1. Simone CB, 2nd, Houshmand S, Kalbasi A, et al. PET-Based Thoracic Radiation Oncology. PET Clin 2016;11:319-32. 10.1016/j.cpet.2016.03.001 - DOI - PubMed
1. Kesarwala AH, Ko CJ, Ning H, et al. Intensity-modulated proton therapy for elective nodal irradiation and involved-field radiation in the definitive treatment of locally advanced non-small-cell lung cancer: a dosimetric study. Clin Lung Cancer 2015;16:237-44. 10.1016/j.cllc.2014.12.001 - DOI - PMC - PubMed