The Long and the Short of It in Cystic Fibrosis Clinical Research Outcomes

Natalie E West¹, Christopher H Goss^{2

3

4}, David P Nichols^{3

4}

Affiliations

¹ 1 Department of Medicine, Johns Hopkins University, Baltimore, Maryland.
² 2 Department of Medicine and.
³ 3 Department of Pediatrics, University of Washington, Seattle, Washington; and.
⁴ 4 Seattle Children's Hospital/Research Institute, Seattle, Washington.

Comment

Natalie E West et al. Ann Am Thorac Soc. 2018 Apr.

. 2018 Apr;15(4):430-431.

doi: 10.1513/AnnalsATS.201801-056ED.

Natalie E West¹, Christopher H Goss^{2

3

4}, David P Nichols^{3

4}

¹ 1 Department of Medicine, Johns Hopkins University, Baltimore, Maryland.
² 2 Department of Medicine and.
³ 3 Department of Pediatrics, University of Washington, Seattle, Washington; and.
⁴ 4 Seattle Children's Hospital/Research Institute, Seattle, Washington.

No abstract available

Comment on

Association of High-Dose Ibuprofen Use, Lung Function Decline, and Long-Term Survival in Children with Cystic Fibrosis.
Konstan MW, VanDevanter DR, Sawicki GS, Pasta DJ, Foreman AJ, Neiman EA, Morgan WJ. Konstan MW, et al. Ann Am Thorac Soc. 2018 Apr;15(4):485-493. doi: 10.1513/AnnalsATS.201706-486OC. Ann Am Thorac Soc. 2018. PMID: 29313709

1. Cystic Fibrosis Foundation. Cystic Fibrosis Foundation Patient Registry, 2016 Annual Data Report. Bethesda, MD: 2017.
1. Konstan MW, VanDevanter DR, Sawicki GS, Pasta DJ, Foreman AJ, Neiman EA, et al. Association of high-dose ibuprofen use, lung function decline, and long-term survival in children with cystic fibrosis. Ann Am Thorac Soc. 2018;15:485–493. - PubMed
1. Fuchs HJ, Borowitz DS, Christiansen DH, Morris EM, Nash ML, Ramsey BW, et al. The Pulmozyme Study Group. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. N Engl J Med. 1994;331:637–642. - PubMed
1. Elkins MR, Robinson M, Rose BR, Harbour C, Moriarty CP, Marks GB, et al. National Hypertonic Saline in Cystic Fibrosis (NHSCF) Study Group. A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. N Engl J Med. 2006;354:229–240. - PubMed
1. Saiman L, Marshall BC, Mayer-Hamblett N, Burns JL, Quittner AL, Cibene DA, et al. Macrolide Study Group. Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA. 2003;290:1749–1756. - PubMed