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Case Reports
. 2019 Mar;38(3):e51-e53.
doi: 10.1097/INF.0000000000002054.

Successful Treatment of a South African Pediatric Case of Acute Liver Failure Caused by Perinatal Transmission of Hepatitis B

Nafiisah Chotun  1 , Silvia Strobele  2 , Tongai Gibson Maponga  1 , Monique Ingrid Andersson  1   3 , Etienne De La Rey Nel  2
Affiliations
Case Reports

Successful Treatment of a South African Pediatric Case of Acute Liver Failure Caused by Perinatal Transmission of Hepatitis B

Nafiisah Chotun et al. Pediatr Infect Dis J. 2019 Mar.

Abstract

We report on the successful treatment of a South African infant with hepatitis B virus (HBV)-induced acute liver failure using lamivudine with no evidence of clinical resistance. Perinatal HBV transmission occurred despite timely HBV vaccination at 6, 10 and 14 weeks, as per South African vaccination schedule, highlighting the need to introduce the birth-dose HBV vaccine in South Africa.

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