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Review
. 2018:152:123-137.
doi: 10.1016/B978-0-444-63849-6.00010-4.

Progressive multifocal leukoencephalopathy

Shaun Zhai  1 , Bruce James Brew  2
Affiliations
Review

Progressive multifocal leukoencephalopathy

Shaun Zhai et al. Handb Clin Neurol. 2018.

Abstract

Progressive multifocal leukoencephalopathy (PML) is a relatively common complication of HIV disease. In this chapter changes to the epidemiology are discussed along with an update in its pathogenesis and treatment. Immune reconstitution inflammatory syndrome is increasingly frequent in PML; accordingly management strategies and prognosis are detailed.

Keywords: HIV; IRIS; JCV; PML; maraviroc; mirtazepine.

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