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. 2017 Oct 13:3:17019.
doi: 10.1038/bdjopen.2017.19. eCollection 2017.

Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial

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Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial

Paul Brady et al. BDJ Open. .

Abstract

Objectives/aims: There has been no dentistry-specific published data supporting the use of monitoring with capnography for dental sedation. Our aim was to determine if adding capnography to standard monitoring during conscious sedation with midazolam would decrease the incidence of hypoxaemia.

Materials and methods: A randomised controlled trial was conducted in which all patients (ASA I and II) received standard monitoring and capnography, but were randomised to whether staff could view the capnography (intervention) or were blinded to it (control). The primary outcome was the incidence of hypoxaemia (SpO2⩽94%).

Results: We enrolled 190 patients, mean age 31 years (range, 14-62 years). There were 93 patients in the capnography group and 97 in the control group. The mean cumulative dose of midazolam titrated was 6.94 mg (s.d., 2.31; range, 3-20 mg). Six (3%) patients, three in each group, required temporary supplemental oxygen. There was no statistically significant difference between the capnography and control groups for the incidence of hypoxaemia: 34.4 vs 39.2% (P=0.4962, OR=0.81, 95% CI: 0.45-1.47).

Conclusions: We were unable to confirm an additive role for capnography to prevent hypoxaemia during conscious sedation with midazolam for patients not routinely administered supplemental oxygen.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Vital signs monitor. Control (blinded capnography) and Capnography (intervention).
Figure 2
Figure 2
CONSORT recrutment diagram.

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