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Editorial
. 2018 Feb;10(2):539-543.
doi: 10.21037/jtd.2018.01.66.

Tumor spread through air space, the clinical implications for T factor and effects on the disease recurrence and prognosis

Takahiro Nakajima  1 , Junichi Morimoto  1 , Ichiro Yoshino  1
Affiliations
Editorial

Tumor spread through air space, the clinical implications for T factor and effects on the disease recurrence and prognosis

Takahiro Nakajima et al. J Thorac Dis. 2018 Feb.
No abstract available

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Conflict of interest statement

Conflicts of Interest: T Nakajima received honoraria and lecture fees from Olympus Medical Systems and AstraZeneca for continuous medical education activities. The other authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Lung cancer in the right upper lobe with occult mediastinal lymph node metastasis. (A) Small pulmonary nodule in the right upper lobe; (B) no enlargement on station 4R; (C) no abnormal accumulation of FDG on station 4R; (D) main tumor was diagnosed as micropapillary predominant adenocarcinoma (H&E staining; magnification 100×); (E) STAS was found in the adjacent alveolar space (H&E staining; magnification 400×); (F) micrometastasis was revealed in the station 4R (H&E staining; magnification 40×). FDG, fluorodeoxyglucose; STAS, spread through air space.
See this image and copyright information in PMC

Comment on

References

    1. Kawakami T, Nabeshima K, Hamasaki M, et al. Small cluster invasion: a possible link between micropapillary pattern and lymph node metastasis in pT1 lung adenocarcinomas. Virchows Arch 2009;454:61-70. 10.1007/s00428-008-0695-5 - DOI - PubMed
    1. Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011;6:244-85. 10.1097/JTO.0b013e318206a221 - DOI - PMC - PubMed
    1. Travis WD, Brambilla E, Nicholson AG, et al. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol 2015;10:1243-60. 10.1097/JTO.0000000000000630 - DOI - PubMed
    1. Travis WD, Brambilla E, Burke AP, et al. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. Fourth edition. Lyon: International Agency for Research on Cancer, 2015. - PubMed
    1. Onozato ML, Kovach AE, Yeap BY, et al. Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis. Am J Surg Pathol 2013;37:287-94. 10.1097/PAS.0b013e31826885fb - DOI - PMC - PubMed

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