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. 2018 Mar 21:13:67-73.
doi: 10.1515/med-2018-0012. eCollection 2018.

Correlation of Retinopathy of Prematurity with Bronchopulmonary Dysplasia

Wojciech Podraza  1 , Beata Michalczuk  2 , Karolina Jezierska  2 , Hanna Domek  2 , Agnieszka Kordek  3 , Beata Łoniewska  3 , Monika Modrzejewska  4 , Joanna Kot  4
Affiliations

Correlation of Retinopathy of Prematurity with Bronchopulmonary Dysplasia

Wojciech Podraza et al. Open Med (Wars). .

Abstract

Retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD) are diseases that occur only in preterm infants. The etiology of these disorders is multifactorial; however, it is believed that some of the factors in children presenting with BPD affect both the initiation and severity of ROP. The aim of the study was to evaluate the degree of clinical severity of ROP in infants with BPD compared to those without BPD.

Methodology: Infants were divided into two groups: the BPD+ study group and BPD- control group. Parameters including the incidence of ROP and its severity were compared.

Results: In neonates with BPD, more severe forms of ROP occurred significantly more frequently than in infants without BPD. Newborns with BPD required significantly longer use of mechanical ventilation; moreover, the number of days in which the concentration of oxygen in the respiratory mixture exceeded 50% was greater in BPD+ children. Children with BPD also received more blood transfusions compared to children without BPD.

Conclusions: Newborns in the BPD+ study group showed advanced stages of ROP more often than newborns in the BPD- control group. The etiology of ROP and BPD is multifactorial; however, our findings suggest oxygen plays a significant role in the development of these diseases.

Keywords: Bronchopulmonary dysplasia; Retinopathy of prematurity.

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Conflict of interest statement

Conflicts of interest: Authors state no conflict of interest.

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