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. 1987 Nov 1;166(5):1573-8.
doi: 10.1084/jem.166.5.1573.

Inhibition of suppressor T lymphocytes by murine interferon beta

D M Sahasrabudhe  1
Affiliations

Inhibition of suppressor T lymphocytes by murine interferon beta

D M Sahasrabudhe. J Exp Med. .

Abstract

We have presented data showing that IFN-beta at 1,000 U/mouse i.v. inhibits the generation of Ts-mediated tolerance to dinitrofluorobenzene (DNFB) and abrogates the transfer of suppression by Ts. We have also presented data showing that IFN-beta up to 10,000 U/mouse i.v. has no adverse effect on sensitization and elicitation. IFN-beta appears to be a suitable agent for evaluation as an adjunct in the immunotherapy of Ts inducing tumors.

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References

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