Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro
- PMID: 2961007
- DOI: 10.1016/0090-6980(87)90262-0
Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro
Abstract
Submicromolar concentrations of human recombinant Lipocortin 1 inhibit the release of prostacyclin from human umbilical artery rings in a dose-dependent fashion. This is the first demonstration that the recombinant protein is effective in human cells.
Similar articles
-
Cocaine use and its effect on umbilical artery prostacyclin production.Prostaglandins. 1990 Sep;40(3):249-57. doi: 10.1016/0090-6980(90)90013-l. Prostaglandins. 1990. PMID: 2247615
-
Inhibition of normal and psoriatic epidermal phospholipase A2 by picomolar concentrations of recombinant human lipocortin I.Br J Dermatol. 1989 Aug;121(2):155-60. doi: 10.1111/j.1365-2133.1989.tb01794.x. Br J Dermatol. 1989. PMID: 2528367
-
Purification and characterization of proteolytic fragments of lipocortin I that inhibit phospholipase A2.J Biol Chem. 1987 Jun 5;262(16):7639-45. J Biol Chem. 1987. PMID: 2953722
-
[Lipocortin--a Ca2+-binding protein which has anti-phospholipase A2 activity].Seikagaku. 1988 Jan;60(1):26-31. Seikagaku. 1988. PMID: 2969024 Review. Japanese. No abstract available.
-
Phospholipase A2 and lipocortin effects.Prog Clin Biol Res. 1990;349:47-54. Prog Clin Biol Res. 1990. PMID: 2144646 Review. No abstract available.
Cited by
-
Biphasic regulation by dexamethasone of IL-1- and LPS-stimulated endothelial prostacyclin production.Agents Actions. 1992 May;36(1-2):70-6. doi: 10.1007/BF01991231. Agents Actions. 1992. PMID: 1414691
-
Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance.J Immunol Res. 2016;2016:8239258. doi: 10.1155/2016/8239258. Epub 2016 Jan 13. J Immunol Res. 2016. PMID: 26885535 Free PMC article. Review.
-
Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.Br J Pharmacol. 1988 Aug;94(4):987-1015. doi: 10.1111/j.1476-5381.1988.tb11614.x. Br J Pharmacol. 1988. PMID: 2974738 Free PMC article. Review. No abstract available.
-
Role of glucocorticoids in neutrophil and endothelial adhesion molecule expression and function.Mediators Inflamm. 1992;1(2):101-6. doi: 10.1155/S0962935192000176. Mediators Inflamm. 1992. PMID: 18475448 Free PMC article.
-
Anti-inflammatory actions of an N-terminal peptide from human lipocortin 1.Br J Pharmacol. 1993 Mar;108(3):573-4. doi: 10.1111/j.1476-5381.1993.tb12843.x. Br J Pharmacol. 1993. PMID: 8467352 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources