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Editorial
. 2018 Feb;6(3):60.
doi: 10.21037/atm.2018.01.02.

Lowering low-density lipoprotein cholesterol by PCSK9 inhibition in patients with diabetes on insulin therapy: is it efficacious and safe?

Affiliations
Editorial

Lowering low-density lipoprotein cholesterol by PCSK9 inhibition in patients with diabetes on insulin therapy: is it efficacious and safe?

Michel Farnier. Ann Transl Med. 2018 Feb.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The author has received grant/research support and speaker’s honoraria from and served as a consultant and advisor for Abbot, Akcea/Ionis, Amgen, AstraZeneca, Eli Lilly, Kowa, Merck and Co, Mylan, Pfizer, Sanofi/Regeneron and Servier.

Comment on

References

    1. Betteridge DJ. Lipid control in patients with diabetes mellitus. Nat Rev Cardiol 2011;8:278-90. 10.1038/nrcardio.2011.23 - DOI - PubMed
    1. Catapano AL, Graham I, De Backer G, et al. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J 2016;37:2999-3058. 10.1093/eurheartj/ehw272 - DOI - PubMed
    1. Cholesterol Treatment Trialists' (CTT) Collaborators , Kearney PM, Blackwell L, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet 2008;371:117-25. 10.1016/S0140-6736(08)60104-X - DOI - PubMed
    1. Shepherd J, Barter P, Carmena R, et al. Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) study. Diabetes Care 2006;29:1220-6. 10.2337/dc05-2465 - DOI - PubMed
    1. Cannon CP, Blazing MA, Giugliano RP, et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med 2015;372:2387-97. 10.1056/NEJMoa1410489 - DOI - PubMed

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